ID A0A0M3HND7_ASCLU Unreviewed; 1436 AA.
AC A0A0M3HND7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 2.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Protein slit {ECO:0000313|WBParaSite:ALUE_0000318201-mRNA-1};
OS Ascaris lumbricoides (Giant roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0000318201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ALUE_0000318201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (MAY-2016) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR WBParaSite; ALUE_0000318201-mRNA-1; ALUE_0000318201-mRNA-1; ALUE_0000318201.
DR Proteomes; UP000036681; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0007399; P:nervous system development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 4.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR006207; Cys_knot_C.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR000372; LRRNT.
DR PANTHER; PTHR45836:SF4; PROTEIN SLIT; 1.
DR PANTHER; PTHR45836; SLIT HOMOLOG; 1.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF12661; hEGF; 2.
DR Pfam; PF02210; Laminin_G_2; 1.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF01463; LRRCT; 2.
DR Pfam; PF01462; LRRNT; 3.
DR SMART; SM00041; CT; 1.
DR SMART; SM00181; EGF; 7.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM00282; LamG; 1.
DR SMART; SM00364; LRR_BAC; 5.
DR SMART; SM00365; LRR_SD22; 9.
DR SMART; SM00369; LRR_TYP; 13.
DR SMART; SM00082; LRRCT; 4.
DR SMART; SM00013; LRRNT; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 6.
DR SUPFAM; SSF52058; L domain-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS01225; CTCK_2; 1.
DR PROSITE; PS00022; EGF_1; 7.
DR PROSITE; PS01186; EGF_2; 6.
DR PROSITE; PS50026; EGF_3; 7.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
DR PROSITE; PS51450; LRR; 5.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 897..932
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 934..971
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 973..1009
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1011..1049
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1051..1087
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1098..1133
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1136..1311
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1314..1352
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1358..1433
FT /note="CTCK"
FT /evidence="ECO:0000259|PROSITE:PS01225"
FT DISULFID 922..931
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 961..970
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 999..1008
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1039..1048
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1077..1086
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1102..1112
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1123..1132
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1318..1328
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1323..1340
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1342..1351
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1436 AA; 159476 MW; 2925B8B9C9B1CC20 CRC64;
MLVNMGMLAR EGQARAKRRG DDAGCNMTVK RAPPNAVARR RGAISPGRST VSTFMFLRSK
YGHMHGTRID ANTERYSSRY ISLVCFREAY RDLQENKISV VRKDDLAALG QLKILQLMDN
QIQMIEDNAF DNLLQLERLR LNRNRLRVLP EGVFINNRNL HRLDLSENFL SVLTDSQLQG
PRSMRNLQLD RNLLTCVDSQ ILSTWTQMEI LTLNANNLST LGEIIPMPNL RVLRLADNPW
LCDCRLRWIK KVISAEPALA SNSRCHRPAH LHSRTIASID EQVMKCSGIE KRAASSCREA
AVCPSVCTCT ESTVDCRDRG LTHIPANLPS SVLELRLEQN QITYIPPRAF HNLYRLKRLD
LSKNSIVEIA PRAFDGLRSL NSLVLYGNSL TDLPSEAFHG LFNIQLLLLN ANKLQCLRKE
TFKNLSNLNL LSLYDNNIKS IANGTFDGLT NLMTLHLARN PIICDCNLEW LAMLLSIRAV
ETSGARCESP KRVARRRLAT LHHSKFRCKG SESYVTARAD ECIIDYGCPV ECSCHGSIVD
CSKRGLTEFP SNIPLFTTEL HMSHNKISSI RNSANFRRLT NLKKLDLSEN RLRHFSASQL
GESSSTLQTL NLSNNSIRCI AEGAMLQLPN IHSIAVGNND FICNCHIADF ANYLRVNGSR
VLDSPKCHEP KHFRGRPIAT VNKDELSCKS AAENVCAENG TYCPAGCICQ GTVVRCSNRA
LKEFPPGIPL ETTELFLDSN DITSIPLAQL NKLYQLAKLD LSHNRITVIE SGAFANLTKL
STLILSYNKL QCLEPAAFSA LSNLRILSLH GNDLSVLPES AFANLTNITH IALGSNALYC
DCHMAWFSKW IKARFVEAGI ARCELPLSTR NQLLLTANEH HFKCEGPLPK TVLAKCDPCI
DNPCRNGAKC KRTHGRSFLC ECVAGFHGRL CEDHIDACYG HPCLNNASCK VIQDGRFTCH
CSKGFEGDRC ETNIDDCVGN KCENGGTCID LINSYECKCP RMYVGQYCEE KLEYCSKKLN
PCQNGGICTA VGDSYSCKCL PGFTGTNCSV NIDDCIDNLC KNNAICVDGV QSYACNCIDG
YTGKFCELAP ISNDLYPNIS PCHAHSCDHG TCRQTESDIV CSCFEGYSGQ RCDRLRAVGF
AEHNAFVALE PWNTAPVGNL TLTLITTEST GIIAYYGDDA HISAELYDGR VKVSFYVGNY
PASHMYSYVT VHDGLPHQLQ VLIEGKTATL KIDSAQPQKV VNSGRKEALE LKSKSSLYLG
GLPPNAAKNA LDAFHVKHAH SFQGCISDVF VNGEAVDFDK VEKRQSIQSG CSHTVDVCRG
VECHKGACIS NATMPLGYEC HCEPGYSGKY CESREVFCTK EKFRRVHEED GCRSVEPIKN
ALCSGWCGEG NECCTAVKGK RRRVKMHCKD GSTNVRTVHI VRKCECATQK KCLRAR
//
