ID   A0A0M3HQT0_ASCLU        Unreviewed;       389 AA.
AC   A0A0M3HQT0;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Ion_trans_2 domain-containing protein {ECO:0000313|WBParaSite:ALUE_0000451701-mRNA-1};
OS   Ascaris lumbricoides (Giant roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0000451701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ALUE_0000451701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC       1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC       ECO:0000256|RuleBase:RU003857}.
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DR   AlphaFoldDB; A0A0M3HQT0; -.
DR   WBParaSite; ALUE_0000451701-mRNA-1; ALUE_0000451701-mRNA-1; ALUE_0000451701.
DR   Proteomes; UP000036681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR003280; 2pore_dom_K_chnl.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR   PANTHER; PTHR11003:SF69; TWIK FAMILY OF POTASSIUM CHANNELS; 1.
DR   Pfam; PF07885; Ion_trans_2; 2.
DR   PRINTS; PR01333; 2POREKCHANEL.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU003857};
KW   Ion transport {ECO:0000256|RuleBase:RU003857};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003857};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857}.
FT   TRANSMEM        16..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        97..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          94..152
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
FT   DOMAIN          185..257
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
SQ   SEQUENCE   389 AA;  44452 MW;  84919902AC32A367 CRC64;
     MKRIDFGNVF QHRKAVVINA ICVLLLIVYV LLGAFVFLLF ERDFDALMRR NTASLKTSCV
     ERILLSRRQL RNVDVRHLAH LITERCIVHM PGPRQQWNFL NAALYAFGVL TTLGYGKIEP
     MTINGRIFAV IYGFVGIPVT VIIFTNFGRY IQQLEEYVRL RLCGKKVERY KDYNSLPAFA
     LFITVFGYLV AGASLLPFLN GKFDFFNGMY WAFLCFTAIE YGELVPENSM YLPIAMAYIC
     LGLSISTIAL DVGSAYVRKL HYVGRKIRNI ANIRIWFGSK SLKVQELINA VAQNMGIEPS
     AMCEIDLESL VKEGKLSRVP QTQMICEGIW PPELVPLFMK DGAFPMFVDD DKPSPHDLSR
     KRRSTSMELK KPSFRLLVIC HSFTPKQRI
//