ID   A0A0M3I0W2_ASCLU        Unreviewed;       238 AA.
AC   A0A0M3I0W2;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Ion_trans_2 domain-containing protein {ECO:0000313|WBParaSite:ALUE_0000982801-mRNA-1};
OS   Ascaris lumbricoides (Giant roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0000982801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ALUE_0000982801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC       1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666}.
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DR   AlphaFoldDB; A0A0M3I0W2; -.
DR   WBParaSite; ALUE_0000982801-mRNA-1; ALUE_0000982801-mRNA-1; ALUE_0000982801.
DR   Proteomes; UP000036681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR003280; 2pore_dom_K_chnl.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR   PANTHER; PTHR11003:SF333; TWIK FAMILY OF POTASSIUM CHANNELS PROTEIN 7; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        32..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          40..111
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
SQ   SEQUENCE   238 AA;  26743 MW;  A59A4B5035B9B865 CRC64;
     MLITVADAGK FIGDALRFLR RRGRSVGVSG PLPVSALLLL MVAYMMIGAV LLHSYEKWTF
     GQAFYWAFIS MSSIGFGDIV PERTEMFPIT IAYILIGLAL ASMCIDTSAA YYIRKIHFFG
     RKMKSAQATV SDLIRLSRRY RLSEKEMNEM SLQSALKHML AACNAYVPED INLIYYIDHP
     SSVFAPFEEN EEIHTIDDDP SPDKQIHSVA FSRDDSAIRD IHTDVVEPPS SIAMILPH
//