ID   A0A0M3I1A2_ASCLU        Unreviewed;       541 AA.
AC   A0A0M3I1A2;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE            EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
OS   Ascaris lumbricoides (Giant roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0001002901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ALUE_0001002901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   AlphaFoldDB; A0A0M3I1A2; -.
DR   WBParaSite; ALUE_0001002901-mRNA-1; ALUE_0001002901-mRNA-1; ALUE_0001002901.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000036681; Unplaced.
DR   GO; GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR043540; RING1/RING2.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR46076:SF3; E3 UBIQUITIN-PROTEIN LIGASE RING1; 1.
DR   PANTHER; PTHR46076; E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER; 1.
DR   Pfam; PF13923; zf-C3HC4_2; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          47..87
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          144..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          235..321
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..173
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  60028 MW;  820C29CB5560EEBD CRC64;
     MSFLILDICT ADIENPDEWE QRRPHKAITD SSEIRISTRL LSAELCCPIC LDLLTTTMTT
     KECLHRFCSE CITTALLRGN KECPTCRKKL VSKRSLRPDP NFDALINKIW PDRQIYEQMQ
     QKAMDIFHQQ SNVEALQKSI EAGMKAQAAN RRQRVQGSYD YERRKRRPRA ENQDRSNNNS
     PESNSPEGSG EGDMDVDQVN ERSDEISVGI LPGTSTGLES DNSFANTNGI SHSAAISSTE
     VSDDSIDSSS DSSSTNSSDS TGSSSTTSTS STSVPTRPNS VAANSMPNAA SLSGTPNGGS
     SIGASGTTYS APVTEDPRPI VPPLSACTLK DRMHKWLEEN PSSPLTPDES MVEQLERRVD
     EDLDITERRA DDEFIEIEAE LLPAKSLFKR PGVAAALLNR RYVRTREDTT MDHLGEFIYQ
     ICCEEMQSLI HADDAENSEP FSMNSLERPT PIAVQRPEHF YVYSRFGGRS VNKIFGNESV
     LSALHTQRRG DHLMIFFDIA PLDMHSKSVL EEIVYDDYLN GMEGVALLRC AGPSWGDSKM
     I
//