ID   A0A0M3I1D3_ASCLU        Unreviewed;       406 AA.
AC   A0A0M3I1D3;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   28-JUN-2023, entry version 16.
DE   SubName: Full=Ion_trans_2 domain-containing protein {ECO:0000313|WBParaSite:ALUE_0001007401-mRNA-1};
OS   Ascaris lumbricoides (Giant roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0001007401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ALUE_0001007401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC       1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666}.
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DR   AlphaFoldDB; A0A0M3I1D3; -.
DR   WBParaSite; ALUE_0001007401-mRNA-1; ALUE_0001007401-mRNA-1; ALUE_0001007401.
DR   Proteomes; UP000036681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 1.
DR   InterPro; IPR003280; 2pore_dom_K_chnl.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR   PANTHER; PTHR11003:SF156; TWIK FAMILY OF POTASSIUM CHANNELS; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 3.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        293..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..356
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        376..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          277..315
FT                   /note="Potassium channel"
FT                   /evidence="ECO:0000259|Pfam:PF07885"
SQ   SEQUENCE   406 AA;  45729 MW;  CC650FF2BDC75ACA CRC64;
     MKRFDVDKSC LFVRRRPASR IMLGRRSSFL RALSSRLTLP HMSDTWSHRL RLVFPHLVLL
     VATLSYAVAG AFVFISIEGP YEIENRNNHL RNIRDLQCTQ EETFELVRLA KLFILENVHP
     PVTDRTKNML EAWLAPSVRT HATYNTYPGH DIAGQIKKSF RSLLHLEADK LDNTTLESII
     DDLIFVSFVA FDAGIRLSDF DENVTLKWSL PSAIFFTTTV LTSIGEALTL TQVLSEHKCA
     KRGILTFVTY AEEEYGDRAS VFVDIKSCKS RDCQFAGYGH LVPISPLGRL FCIGYAFLGI
     PLTLITIADV AKFLSDLATS AYRNPLNEEV SGRTRLCIVA ILLFYMTIAA LIFSVFETAW
     SFLDSFYFCL ITVADSTMII AVNMGLSALN CHLICLILVS ISHSDR
//