ID A0A0M3IC60_ASCLU Unreviewed; 612 AA.
AC A0A0M3IC60;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 2.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Cytoplasmic intermediate filament protein {ECO:0000313|WBParaSite:ALUE_0001543201-mRNA-1};
OS Ascaris lumbricoides (Giant roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0001543201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ALUE_0001543201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (MAY-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|PIRNR:PIRNR005546}.
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DR AlphaFoldDB; A0A0M3IC60; -.
DR WBParaSite; ALUE_0001543201-mRNA-1; ALUE_0001543201-mRNA-1; ALUE_0001543201.
DR Proteomes; UP000036681; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 2.60.40.1260; Lamin Tail domain; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR016451; Intermed_filament_ifa/ifb.
DR InterPro; IPR001322; Lamin_tail_dom.
DR InterPro; IPR036415; Lamin_tail_dom_sf.
DR PANTHER; PTHR45721:SF12; INTERMEDIATE FILAMENT PROTEIN IFA-1; 1.
DR PANTHER; PTHR45721; LAMIN DM0-RELATED; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF00932; LTD; 1.
DR PIRSF; PIRSF005546; Intermed_filamnt_Ifb-2; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR SUPFAM; SSF74853; Lamin A/C globular tail domain; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
DR PROSITE; PS51841; LTD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|PIRNR:PIRNR005546};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|PIRNR:PIRNR005546}.
FT DOMAIN 92..445
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT DOMAIN 486..604
FT /note="LTD"
FT /evidence="ECO:0000259|PROSITE:PS51841"
FT REGION 55..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 343..377
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 403..444
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 458..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 69771 MW; 6C08C518F51AD752 CRC64;
MKSTTTKELK TTSTEIKIAN RVGVEQMRSS SYHSTYLMSP ASGYRSESVY NTSVGGLYGP
GSRPERLTSD RRSLSGSSLS AAVSIRDSRE REKKEISDLN DRLASYIEKV RFLDAQNRKM
NNDLELFRAR MGKDTLSTKA MYEGEIAEAR KLIAATEVER GELEKQIPKL QAEITEYRKK
YDDALRGHDV DKKKIDDLIV NFTGIENESN LLRRRIAELE GEVGELKKIN VTDNSNFTRT
RTAIDQESLS RIDFQNKAQM MLEEIEFIRR EHDQELSDLH AVAARDTTSE NREYFKNELA
SAIRTIRGDY DQIMAGHRSD IESWYHLKVQ EICTASNRQT LERGYAKEEV KRLRNQLTDL
RTRLADFEGR NSLLEKQVGD LNFQMEDEQK TYEFTLKERD EQTRRVREEC EALMLELQNL
LDTKQTLEAE IVQYRKLLEG EESRAGLRRL AQQVKTSEIS VTDGGSHSSI VESSEKTSKE
MGETTSKIHY HATAKGNLSI QDASVDGKFI VIENTSPTKE ENIGEWQIKR SADNGPEVVF
TFPKGFILKP LKTVKIWARD QGGEDKPPDQ LVFEKEDSFG FGSNAKTVLI NASGEERASH
LQTTTQSTVI YA
//
