ID A0A0M3IFS7_ASCLU Unreviewed; 685 AA.
AC A0A0M3IFS7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Protein kinase domain-containing protein {ECO:0000313|WBParaSite:ALUE_0001709101-mRNA-1};
OS Ascaris lumbricoides (Giant roundworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0001709101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ALUE_0001709101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
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DR AlphaFoldDB; A0A0M3IFS7; -.
DR WBParaSite; ALUE_0001709101-mRNA-1; ALUE_0001709101-mRNA-1; ALUE_0001709101.
DR Proteomes; UP000036681; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR PANTHER; PTHR24203; ANKYRIN REPEAT FAMILY PROTEIN; 1.
DR PANTHER; PTHR24203:SF45; DIEGO, ISOFORM A; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 10.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50297; ANK_REP_REGION; 6.
DR PROSITE; PS50088; ANK_REPEAT; 6.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141}.
FT REPEAT 103..135
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 169..201
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 202..234
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 235..256
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 273..294
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 343..375
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 509..685
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 536
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 685 AA; 74479 MW; 14115B9A1D15A55D CRC64;
ELKKKISEGY AVVRSRLNDD VKPRFDSWNV VQNACFQGSA KCLEEHLTLA VLDERTEDHH
LSLLHLICAG HSEQQASKVA ILLNKCGDDD AKRRALLNHI TKNGFSALHI CIYKSEVATA
ESLLLAGADA NLAGRSELPP LNLAAMCANM ELVERLIGAG AILHACDFVN FTALHCATYF
AHEKVVRLLL RRGADPNYSG GVRDRPLHLA SSKGHVGIVS ALLEAGADPT LADDEGNTSL
HFAAKTGHVG IIDLLLLKIG AGHQELALKT NVYGDTPLHA ACYAGRLEAA KRLIAIAGSN
TLNMENVFSE TPLHAACTSG RNLELVAFLL KQPGVDANYQ GQDGHTALHS ACYHGHLRFV
QFLLDSGADQ SLTARAVDYP LSPTVATSGA FPVTSTIAHT MFALSRPESA GSVGDSSISS
TLSLCDDQQQ TPVIWAYEKG HDQIVALLKH YANKRPDSDV CSEYSSGDSS YTPLPSPLGR
LRSMTKEKAE ILQLRASLAN SFHLSLSDVD FQEAVGSGSF GKVYKGTYRG KTVAIKRYRA
VAYGAKSEVD MFCREVSILC KLQHPNVISL VGACLDDPSQ FAIITEFVSN GSLFSLLHEQ
KRVLEMALRL NIGIDVARGM RYLHELAERP VIHRDLNSHN ILLHENGRAV VADFGESRFM
AQRDSDNMTK QPGVISIYLL GNFFF
//
