ID A0A0M3IZ92_ANISI Unreviewed; 440 AA.
AC A0A0M3IZ92;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=FERM domain-containing protein {ECO:0000313|WBParaSite:ASIM_0000057301-mRNA-1};
GN ORFNames=ASIM_LOCUS475 {ECO:0000313|EMBL:VDK17749.1};
OS Anisakis simplex (Herring worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC Anisakis simplex complex.
OX NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0000057301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ASIM_0000057301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK17749.1, ECO:0000313|Proteomes:UP000267096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRR01000305; VDK17749.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M3IZ92; -.
DR WBParaSite; ASIM_0000057301-mRNA-1; ASIM_0000057301-mRNA-1; ASIM_0000057301.
DR Proteomes; UP000036680; Unplaced.
DR Proteomes; UP000267096; Unassembled WGS sequence.
DR GO; GO:0070161; C:anchoring junction; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13190; FERM_C_FAK1; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR049385; FAK1-like_FERM_C.
DR InterPro; IPR041784; FAK1/PYK2_FERM_C.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46221; FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR PANTHER; PTHR46221:SF11; NON-SPECIFIC PROTEIN-TYROSINE KINASE; 1.
DR Pfam; PF21477; FERM_C_FAK1; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000267096}.
FT DOMAIN 1..286
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT BINDING 380
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 440 AA; 50241 MW; 887B0CDC18E06BBA CRC64;
MAHTTTNSDC YWLHGSYTMR NIYEKYFSNA ASCSQLRFEL RLRFVPSDLQ EMYQTQAEAF
MFLHEQVLAD YLAQVSWRLP NETAMELASL QVRKRLGNLN VLAIEKNVSF EELEAEGILT
RYLPETIVVN TKPKALRKSL LSAVKRNAAL SPTECVLRFL KIVLKVSQFD VEIFRASLGA
GWTSPVDILV GMRIGISFNT EIQCAPTLIT QLHNITEISV RKLDEISEKA IVQLRVTGSS
QPLVHEDFSY FAYCIEFQSI TLPNWLIAES LAHLIDGYQM LLSQQNSVWT PRELKCHAVA
SEFFAQCESL SLPRRQNGDQ RADESNNAME IHRTLSLNID LHIDRSRVSL EELLGDGQFG
NVYRGTYTQE SNTSQAVAVK VCKVDSEPLE MQNFLEEACK CQSSYIYAQI LCDHNIYFLV
PFEFSAQEHN SGEKRMHTMR
//
