ID   A0A0M3JRV8_ANISI        Unreviewed;       916 AA.
AC   A0A0M3JRV8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=SSD domain-containing protein {ECO:0000313|WBParaSite:ASIM_0001066401-mRNA-1};
GN   ORFNames=ASIM_LOCUS10222 {ECO:0000313|EMBL:VDK42557.1};
OS   Anisakis simplex (Herring worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC   Anisakis simplex complex.
OX   NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001066401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ASIM_0001066401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDK42557.1, ECO:0000313|Proteomes:UP000267096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   EMBL; UYRR01030989; VDK42557.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M3JRV8; -.
DR   WBParaSite; ASIM_0001066401-mRNA-1; ASIM_0001066401-mRNA-1; ASIM_0001066401.
DR   Proteomes; UP000036680; Unplaced.
DR   Proteomes; UP000267096; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   PANTHER; PTHR10796:SF124; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267096};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        38..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        439..467
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        546..570
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        769..784
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        791..813
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        819..842
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          288..467
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   916 AA;  104150 MW;  27BD8868CB08666B CRC64;
     MTISSKDPTK TSASCRWAPL EKPLANLLGR YCRFVARYPW PFIIAPTLLT CFLSTGIFLN
     FEIVRGVRYL YAPLNAKWKF EEEVLHRNWA ATDQQFYPGK DIMRRKGLYL MVQAKDYGSV
     LRRSYANEFV RLLDWISTEH FKTDDGIEYS YRNICLRFQN DCFTNAHARL LGEIFSKGDQ
     DALNVTYPKF YSQYSTEPID LSLTLGGIET NSRQRLLYAS TWMILYQLKQ HSDLMMKLSS
     HFEIAVSERI NSGHIPTSLF NVYYFHSDTF ELELAESNRR LIPSFLLTFI ILSIFSVMCT
     FNVNILPMRN GSFVTVVDWV TSKPLMGIVG VITTLMAIVS ATGLLLLFKV TFVDMATVMP
     FLSLTIGIDD TFLMLAAWHE TKTAIRHCYP PCEGSSSVSS VVEDRIERAM RHAAVSISIT
     SLTDAIAFII GSIAPLPAVI YFCYYSSAAI CFIFAYSLTI FVAFLAIQGR WEESYRHCVL
     HLPTEPFEHI ETVSFMQRYL NMGSRTSVRE IHIHTDLNGS PLSTSSRSEK IALENRLWYQ
     RFFEDFYAPF IANTLIQTIA LISFIVYLAI ACWGTKNVKV GFDLMSIIQK DSPPRRFLEI
     RNELFVNVAT KVDVAVMHPP NMGDHNARIR FFEALNELEQ TNCSVGQNGT DFWYFAYQRF
     VSRLGFGDSW ATLNQNETEF NLNLKSFLMT NERYAHDILL YENGSMRAFR LSVQLINKQP
     SDEHIILCAK LFREAAAKYE SEFNITTYTQ LWALADQFEI MWPQTMQDLY ISIAVMIPVS
     LLFIPQPLCA LVIALNIASI AVGVIGFMTL WSVHLDATSM ITIAMSVGFS VDFAAHITYG
     YMTETKKNEI SDAHSTAAPY QQLVKALGAV GWPVTQASVS VLLGIMTLAT LDSYVVKTCF
     KTILIVIIIG KMLIQS
//