ID   A0A0M3JSC5_ANISI        Unreviewed;       491 AA.
AC   A0A0M3JSC5;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   13-SEP-2023, entry version 24.
DE   SubName: Full=Plug_translocon domain-containing protein {ECO:0000313|WBParaSite:ASIM_0001086701-mRNA-1};
GN   ORFNames=ASIM_LOCUS10425 {ECO:0000313|EMBL:VDK42960.1};
OS   Anisakis simplex (Herring worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC   Anisakis simplex complex.
OX   NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001086701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ASIM_0001086701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDK42960.1, ECO:0000313|Proteomes:UP000267096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU003484}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003484}.
CC   -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family.
CC       {ECO:0000256|ARBA:ARBA00005751, ECO:0000256|RuleBase:RU004349}.
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DR   EMBL; UYRR01030998; VDK42960.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M3JSC5; -.
DR   WBParaSite; ASIM_0001086701-mRNA-1; ASIM_0001086701-mRNA-1; ASIM_0001086701.
DR   Proteomes; UP000036680; Unplaced.
DR   Proteomes; UP000267096; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3370.10; SecY subunit domain; 1.
DR   InterPro; IPR002208; SecY/SEC61-alpha.
DR   InterPro; IPR030659; SecY_CS.
DR   InterPro; IPR023201; SecY_dom_sf.
DR   InterPro; IPR019561; Translocon_Sec61/SecY_plug_dom.
DR   NCBIfam; TIGR00967; 3a0501s007; 1.
DR   PANTHER; PTHR10906:SF1; DSEC61ALPHA; 1.
DR   PANTHER; PTHR10906; SECY/SEC61-ALPHA FAMILY MEMBER; 1.
DR   Pfam; PF10559; Plug_translocon; 1.
DR   Pfam; PF00344; SecY; 1.
DR   PIRSF; PIRSF004557; SecY; 1.
DR   PRINTS; PR00303; SECYTRNLCASE.
DR   SUPFAM; SSF103491; Preprotein translocase SecY subunit; 1.
DR   PROSITE; PS00755; SECY_1; 1.
DR   PROSITE; PS00756; SECY_2; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|RuleBase:RU003484};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267096};
KW   Translocation {ECO:0000256|ARBA:ARBA00023010,
KW   ECO:0000256|RuleBase:RU003484};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003484};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003484}.
FT   TRANSMEM        80..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        165..184
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        260..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        377..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        428..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        452..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          87..121
FT                   /note="Translocon Sec61/SecY plug"
FT                   /evidence="ECO:0000259|Pfam:PF10559"
SQ   SEQUENCE   491 AA;  54028 MW;  928BA3D4875BA8E6 CRC64;
     MENPLELNLS DSKAIESKRG KNSTVSRKTL KSCRWVTEHI CFEKVPAMGI KFLEFVKPFC
     GFVPEVSKPE RKIQFREKML WTAITLFVFL VCCQIPLFGI MSTDSADPFY WLRVILASNR
     GTLMELGISP IVTSGLIMQL LAGAKIIEVG DTPKERALFN GAQKLFGMVI TVGQAIVYVA
     SGLYGDPSEI GAGICLLIVI QLVVAGLIVL LLDELLQKGY GLGSGISLFI ATNICETIVW
     KAFSPATMNT AFYRPNLPNL MNLMATVLVF AVVIYFQGFR VDLPIKSARY RGQYSSYPIK
     LFYTSNIPII LQSALVSNLY VISQMLAAKF GGNILVNLLG TWSDAGGYRS YPTGGICYFL
     SPPETLAHVM EDPIHCIIYI VFMLGSCAFF SKTWIDVSGS SAKDVAKQLK EQQMVMRGHR
     EKSMIHELNR YIPTAAAFGG LCIGALSVTA DFMGAIGSGT GILLAVTIIY QYFEIFVKEQ
     QEMGGVAGMF F
//