ID A0A0M3JV21_ANISI Unreviewed; 486 AA.
AC A0A0M3JV21;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=ASIM_LOCUS11522 {ECO:0000313|EMBL:VDK45253.1};
OS Anisakis simplex (Herring worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC Anisakis simplex complex.
OX NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001205601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ASIM_0001205601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK45253.1, ECO:0000313|Proteomes:UP000267096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
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DR EMBL; UYRR01031078; VDK45253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M3JV21; -.
DR WBParaSite; ASIM_0001205601-mRNA-1; ASIM_0001205601-mRNA-1; ASIM_0001205601.
DR Proteomes; UP000036680; Unplaced.
DR Proteomes; UP000267096; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd20344; BRcat_RBR_TRIAD1; 1.
DR CDD; cd20360; Rcat_RBR_TRIAD1; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 2.20.25.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR047555; BRcat_RBR_TRIAD1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR047556; Rcat_RBR_TRIAD1.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22771; CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR22771:SF4; CULLIN-9; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000267096};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 127..338
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 56388 MW; E91CB22EC9F8FE59 CRC64;
MNSNESVNDS GSGSDDDADY YLDDYYNGTE YDVGESCDIE TAPENDDPEY IEYNCLTVPQ
VERLLNETIE RVAGLLNISQ SISKLLLYMH KWNEAALVDQ YKSNPKKTLT ECKICSISNG
GGLKKENCAR CGVCARWRRD CGKMSALHCG HEFCVACWQA YTETQLSNAV SIRMGCMASE
CALLCPEDFV MEVLSDRNDL RAKYKEFVFR DLVTSHPELR FCPGRDCQMI VMAKSQKAKR
VTCVKCRTSF CVLCGNDYHA PTSCETIRMW LIKCADDSET ANYISAHTKD CPNCHSCIEK
NGGCNHMQCA KCKHHFCWMC FGDWKTHGSE YYECSRYKEN PSVAQEANHV KARRALEKYL
HYYERYENHH KSLKLEEELR NSIMRKIDEK VNGHEGTWID WQHLHRAATL LTKCRYTLQY
TYPYAYYMEN GPRKQLFEYQ QAQLEKEIEE LSWKVERAES TERGDLESQM HVAECKRRTL
LQDFFD
//
