ID   A0A0M3K119_ANISI        Unreviewed;       416 AA.
AC   A0A0M3K119;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=COP9 signalosome complex subunit 4 {ECO:0000256|ARBA:ARBA00014881};
GN   ORFNames=ASIM_LOCUS13954 {ECO:0000313|EMBL:VDK51023.1};
OS   Anisakis simplex (Herring worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC   Anisakis simplex complex.
OX   NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001454401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ASIM_0001454401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDK51023.1, ECO:0000313|Proteomes:UP000267096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CSN4 family.
CC       {ECO:0000256|ARBA:ARBA00010417}.
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DR   EMBL; UYRR01031560; VDK51023.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M3K119; -.
DR   WBParaSite; ASIM_0001454401-mRNA-1; ASIM_0001454401-mRNA-1; ASIM_0001454401.
DR   Proteomes; UP000036680; Unplaced.
DR   Proteomes; UP000267096; Unassembled WGS sequence.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR040134; PSMD12/CSN4.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10855; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR   PANTHER; PTHR10855:SF2; COP9 SIGNALOSOME COMPLEX SUBUNIT 4; 1.
DR   Pfam; PF01399; PCI; 1.
DR   SMART; SM00088; PINT; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000267096}.
FT   DOMAIN          202..370
FT                   /note="PCI"
FT                   /evidence="ECO:0000259|PROSITE:PS50250"
SQ   SEQUENCE   416 AA;  47349 MW;  3509711BEBC6A0AD CRC64;
     MSDDITTLVS RIFSGEPDHK VQSEKIKNML MEVLSSVGSS DEESISDRVN QLAAAVVNQE
     SISMVVSRQF VSDVVVAMEQ LPHNIVKRMA IGLLATIHSR HISYEEQAAQ LRFKLADIYE
     MEGENKQAAK TLMAIPLETG QRSYPADLKM RTYLRIAQLA LEYGDAADAE AFVNRASMLQ
     NDAKNEQLNI MYKAQYARVL DHRRKFIEAA QRYYELSLVP VLTNSEKMQA LMNAVSCAIL
     ASPGIQRSRM LTALFKDERC ERLPSHSVLQ KMHLERLIKH DEVSEFEKSL SAHQREVHDG
     CSILQRAVIE HNVIAISNIF MNISFDDLAQ LLEINVKRAE KVTWQMIAEK RINGSIDQLD
     RVVRFKRKDA LVEWDEQIGE LCQHVNHIVD MILDEHKEWA EQRIESSRSG TGITAS
//