ID A0A0M3QV49_DROBS Unreviewed; 751 AA.
AC A0A0M3QV49;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN ORFNames=Dbus_chr2Rg1342 {ECO:0000313|EMBL:ALC41763.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC41763.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC41763.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC41763.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC 2.A.22) family. {ECO:0000256|ARBA:ARBA00006459,
CC ECO:0000256|RuleBase:RU003732}.
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DR EMBL; CP012524; ALC41763.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M3QV49; -.
DR SMR; A0A0M3QV49; -.
DR OMA; LPWSKCE; -.
DR Proteomes; UP000494163; Chromosome 2r sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616:SF318; FI17140P1-RELATED; 1.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 1.
DR PRINTS; PR00176; NANEUSMPORT.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000494163};
KW Symport {ECO:0000256|ARBA:ARBA00022847, ECO:0000256|RuleBase:RU003732};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003732};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT TRANSMEM 128..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 350..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..551
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 729..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 729..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 751 AA; 83414 MW; DF1B019EA0733361 CRC64;
MDKKSKTKSK TKSLKPNKES STQLEVDSWE QNEELLISCD KERRGRKSPQ TAGAGAVICP
GNASAKAAAT ASKDSTVKAT TAPQLSTTPT AISIAGCASG TALVTLDDVL ATEATEPERG
NWTGRFDFLL SLLGYSVGLG NVWRFPYLCY NNGGGAFLIP FTIMLIIAGL PLMFMELSFG
QYAALGPVAV YRRFCPLFRG LGTGMVLVSA IVMLYYNLII AWTIFYMFAS FRTQLPWQNC
EPEWSTEHCF SYAMADQCDA VNGTYYLRNC YNATYADEHN ITGLALHALK RPPAEEYFNN
FVLGLSSGIE ETGSIKYSLA ACLLIAWIIV FLCLCKGVQS SGKVVYFTAL FPYLVLVILF
FRGVTLPGAS TGILFYLSPD WAQLANAQVW GDAAVQIFFA LSPAWGGLIT LSSYNKFSNN
CYKDSLIVAF CNIATSFFAG LVIFSIIGFL AHELEVEVEK VVDQGAGLAF IVYPEVVTRL
PISPVWSVLF FVMLLTLGLD SQFALMETVT TAILDKFPNL RQFKVWVVLF VAVFGYVGGL
GFTTNSGMYW LQLMDKYAAN WSVLLIAISE CVLIAWIYGS QRFLNDIQGM IGKRSRCWNI
FWSTMWRYIT PATLLFILFF NWVEYKPAQY GHYVYPLWAD TVGWFIGLLP VLIIFLVGLQ
QFCKASKQLT IKERFKHLLK PTAEWGPAGR PCVNLHAERY QSQNYDGVTN TQILISSAPI
EDGIYEETIN DSGNGNANGN ENGYRDDAMQ L
//
