ID A0A0M3QYM4_DROBS Unreviewed; 875 AA.
AC A0A0M3QYM4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Scm {ECO:0000313|EMBL:ALC47933.1};
GN ORFNames=Dbus_chr3Rg2683 {ECO:0000313|EMBL:ALC47933.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC47933.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC47933.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC47933.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
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DR EMBL; CP012526; ALC47933.1; -; Genomic_DNA.
DR RefSeq; XP_017849409.1; XM_017993920.1.
DR AlphaFoldDB; A0A0M3QYM4; -.
DR SMR; A0A0M3QYM4; -.
DR STRING; 30019.A0A0M3QYM4; -.
DR GeneID; 108604442; -.
DR OMA; NKEFCSM; -.
DR OrthoDB; 2908161at2759; -.
DR Proteomes; UP000494163; Chromosome 3r sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20110; MBT_dScm_rpt2; 1.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR010507; Znf_MYM.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF132; POLYCOMB PROTEIN SCM; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR Pfam; PF06467; zf-FCS; 1.
DR SMART; SM00561; MBT; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000494163};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 41..80
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT REPEAT 162..260
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 268..369
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 525..690
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..690
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 93717 MW; 7DDED8163E5A15DC CRC64;
MSGGRDSSAS AISGTNGNSA ATNSSSTATT TTPQTPTQRA RGRPAKRATC TWCGEGKLAL
QYVLPTQTGK KEFCSETCIA EFRKAYSKGA CTQCDNVIRE GAPNKEFCSM MCMNKHQKKN
GSTRHHAGGA GAAGVLDSDR KSISSGAPAP TGPFQYESFH VFDWDAYLEE TGSEAAPAEC
FKQALNPPTN DFKIGMKLEA LDPRNVTSTC IATVVGVLGS RLRLRLDGSD SQNDFWRLVD
STEIHAIGHC EKNGGMLQPP LGFRMNASSW PGYLCKILNN AMVAPEDIFQ PEPSTPMDNL
FKVGQKLEAV DKKNPQLICC ATVDAIKDDQ IHVTFDGWRG AFDYWCNYRS RDIFPAGWCA
RSCHPMQPPG HKSRMDSSSG KQRCPRPRYT VIAESDAMVP ASPVTAHFHP NCKGGPFISS
SKLPSMVTGP THQTLAKLCL QEVLAASTDT QQLSKLLFSL EGDVHIVTAA GKNFTVKIPS
PLRMKDDDSL AQFIETLCTT CRACANLISL VPDTEECKKC ANSRKRQLAQ TATPPSSPVL
ADKRGRQSKS TTPTPIATTT SPIDKPVIVK EELDVKAQQP QSSSKSLASK ESLNHNSHSS
SNSKKSNCNN NGSITKLSIK TEPNGMTFTA TSMGPTSSSQ SQTQALRKVR FVHHSTINNK
QNNNGKSNQE TNSSSSTTPP TNSCNSSSSL AGGTASASSI GKYLAPLVAE VHPEQLTSKL
QSNYYKSPTT LSSSASFPSS VSTPFTASQS ACSAAPAASA AKAATAPVAA AVSSSYASMA
ITSPLNTPTA SAALSHLRAQ PVDWTIEEVI QYIETNDNTL AVHGDLFRKH EIDGKALLLL
NSEMMMKYMG LKLGPALKIC NLVNKVNGRR NNLAL
//
