ID A0A0M3R9C1_9BACI Unreviewed; 1490 AA.
AC A0A0M3R9C1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Thioester reductase {ECO:0000313|EMBL:ALC81182.1};
GN ORFNames=AM592_05905 {ECO:0000313|EMBL:ALC81182.1};
OS Bacillus gobiensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1441095 {ECO:0000313|EMBL:ALC81182.1, ECO:0000313|Proteomes:UP000067625};
RN [1] {ECO:0000313|Proteomes:UP000067625}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-4402 {ECO:0000313|Proteomes:UP000067625};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Genome sequencing project for genomic taxonomy and phylogenomics of
RT Bacillus-like bacteria.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ALC81182.1, ECO:0000313|Proteomes:UP000067625}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-4402 {ECO:0000313|EMBL:ALC81182.1,
RC ECO:0000313|Proteomes:UP000067625};
RX PubMed=26530456; DOI=10.1099/ijsem.0.000729;
RA Liu B., Liu G.H., Cetin S., Schumann P., Pan Z.Z., Chen Q.Q.;
RT "Bacillus gobiensis sp. nov., isolated from a soil sample.";
RL Int. J. Syst. Evol. Microbiol. 66:379-384(2016).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP012600; ALC81182.1; -; Genomic_DNA.
DR STRING; 1441095.AM592_05905; -.
DR PATRIC; fig|1441095.3.peg.1290; -.
DR OrthoDB; 9765680at2; -.
DR Proteomes; UP000067625; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd19534; E_NRPS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020459; AMP-binding.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR PRINTS; PR00154; AMPBINDING.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000067625}.
FT DOMAIN 948..1022
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1490 AA; 171823 MW; C8ABEBC1E9ACD4AC CRC64;
MNQKECFSLT HPQKRIWYME NINPGEPLHN IGGIVGIKGN VDFTVLEEAI NLFIKSNDGI
RHHIVEADGN VRQYVEEYRK FHVRHVEFSC REDMDVWVRQ EAGKPFPLYE SNLFDFAFFT
IRNSGVGGYF VKVHHMISDG WSMNLLTEQI CNTYMKRLNG ERIADQQRES YFSYLKKEEA
YAASKRFEKN KQFWNEKFSV LPESLKSELV CADGKRKTFR LSDSQSNAIK QFAADHQVSV
YAFFVALYSI YLHKATMQDE LIIGMPVFNR SGKVEKNIFG MFTSTMPFRY RTDVDVSVRE
MVQTIHQELL RCYFHQKYPY ELLIQDLGLK QRGLGDLFDT CINYYNTSLP NKLDGSPIEN
EEFYNGKQIY SLQVIVREWS RSGGFDLDFD YKVQTFNEHQ IDHMYLSFTH IIDQILKFPN
QLLKETEIIS EKLKNELLDD FNRTDTDYQK EKTIHQLFEE QAEKTPNKAA LILENEQLTY
RELNEKSNQL ARYLIKKKVQ KGTIVGISTK HSIETIIGIL GILKAGAAYV PIDPDYPSDR
IHYMLQDSGI SILLCNLDRS LFPYHIEVIE LNSADIYKGD SSKLHVLSDP TDLAYIIYTS
GSTGKPKGVM IEHQGLVNYI CWAKKEYVGT SENEIFPFYS SLAFDLTVTS IFVPLISGNK
IVIYPADDNQ YVLYKIIREK LSTIIKLTPS HLSLLQDTAY DSSTIHTFIV GGEDLSVSLA
KRIQNRFGRH IKIFNEYGPT ETVVGCMIHQ FDAEKDTGSS VPIGRPIQNT KIYLLDADLQ
PLPVGAVGEI FISGDGVSRG YLNKPELTQE KFFKNPYSIG ERIYRSGDLA RFVDENKIEY
AGRIDHQIKI RGYRIERSEI ENNLRSHPSI RDAIVIDREN NGGNRSLFAY YTEKQKVDVP
EIIRYLKDRL PSYMIPSFFV PLKEIPLTIN AKVNKEALPD PEITRWGDPD SEIEENLASV
LRDVLGVDQV GMQDNFYHLG GDSIKAIQMA SMLSDKGLRL KTKDILANPV IEDMTMFMEK
SDNKMSESSN APCSGVIQPL PSASWFFSQN LDNINHYTQS VLLKVTDDIN IELLESALRL
LIGRHDAFRL NYRKETKELY FNESGFDQKI ELKSFDLSND PDSEQFKRIE DIGEMLKASF
RIEHDLLLKA CMFDLGSKGK RVFLTAHHLA VDGISWRIIL EDLNRIYEQM EEQREVYLPP
KTDSIKQWAM ELQTFSKRIS DKEKQYWRDV YRHQNETITD FDLGQDRLES CESMVLMLSE
EETTDLLQKA NEAYLTKADE LMIIALSIVT SDFFKKNQVL LEIEGHGRED LGNEIDVSRT
VGWFTSLYPV LLKVEETDLS HQIKQGKEQL RQIPSKGLSH GVMKYLAGDL PGDNHKYIRF
NYLGDFHASF SSGLFEFAEE YTGRESSHTN ELDCLIDIIA YMVNGKLRFS LTYSQNKFKR
ESISQFAKAY MNQMRDVILH CCQRNHAEFT PSDFEAANLS SEDLENIFSE
//
