ID A0A0M3V616_9NOSO Unreviewed; 716 AA.
AC A0A0M3V616;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ACX27_21870 {ECO:0000313|EMBL:ALF54873.1};
OS Nostoc piscinale CENA21.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=224013 {ECO:0000313|EMBL:ALF54873.1, ECO:0000313|Proteomes:UP000062645};
RN [1] {ECO:0000313|Proteomes:UP000062645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CENA21 {ECO:0000313|Proteomes:UP000062645};
RA Leao T.F., Leao P.N., Guimaraes P.I., de Melo A.G.C., Ramos R.T.J.,
RA Silva A., Fiore M.F., Schneider M.P.C.;
RT "Genome Of Nitrogen-Fixing Cyanobacterium Nostoc piscinale CENA21 From
RT Solimoes/Amazon River Floodplain Sediments And Comparative Genomics To
RT Uncover Biosynthetic Natural Products Potential.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ALF54873.1, ECO:0000313|Proteomes:UP000062645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CENA21 {ECO:0000313|EMBL:ALF54873.1,
RC ECO:0000313|Proteomes:UP000062645};
RX PubMed=27034496;
RA Leao T., Guimaraes P.I., de Melo A.G., Ramos R.T., Leao P.N., Silva A.,
RA Fiore M.F., Schneider M.P.;
RT "Draft Genome Sequence of the N2-Fixing Cyanobacterium Nostoc piscinale
RT CENA21, Isolated from the Brazilian Amazon Floodplain.";
RL Genome Announc. 4:0-0(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP012036; ALF54873.1; -; Genomic_DNA.
DR RefSeq; WP_062295522.1; NZ_CP012036.1.
DR AlphaFoldDB; A0A0M3V616; -.
DR STRING; 224013.ACX27_21870; -.
DR PATRIC; fig|224013.5.peg.5246; -.
DR OrthoDB; 510512at2; -.
DR Proteomes; UP000062645; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd16934; HATPase_RsbT-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43547:SF2; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE C; 1.
DR PANTHER; PTHR43547; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 2.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF52172; CheY-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ALF54873.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000313|EMBL:ALF54873.1}.
FT DOMAIN 223..442
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 464..577
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 584..700
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 158..195
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 513
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
FT MOD_RES 633
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 716 AA; 79317 MW; BD21C1B90DBC2225 CRC64;
MTTIFTVEIQ YEQDVVQARQ RTREISEQLG FAAQDQARLA TAVSEIARNA FQYARGGTVE
FSVAGEPQTF VIRIQDQGQG IPHLAEVLAG RYTSSTGMGL GIMGSRKLID VFEIESLPGQ
GTTVVMSKKL SKRTPNFTDS QLQQIRETVM ERSPQNPYEE IQRQNQELLR AMAELRKREE
ELTQINRELE DTNRGVVALY AELDEKASSL QKVNELKTRF LSNMSHEFRT PLNSILSLSR
MLLAQMDGDL TVEQEKQVTF IQKAANGLSE LVNDLLDLAK VEAGKIEVRP SSFEVSDLFG
TLRGMLRPLL VQESSVALIV EEPEGIAPLY TDEGKVAQIL RNLVSNALKF TQQGEVRVSA
VQNDHTVTFS VSDTGIGIAI ADQERIFEDF IQIESSLQKQ VKGTGLGLPL SHKLAELLGG
SISVKSELGQ GSTFTASIPI TYPYTTEFPT RLQPIASLEP TRLPILAVED HPETLFIYEN
HLQQSTYQLI ATRTLAQARQ VLQQVRPMAI LLDIMLEGQN GWTFLRELKG DETTSTIPVL
VITIIDNEKQ ALALGANGFL IKPVDRLQLL IKLNTLINQN KPQKILLIDD DPAYRYLMKQ
LLVNTPLSIL EATNGREGLA LAQREQPTAI VLDLEMPEFS GFDVLKELKH NSVTSSIPVI
IHSSAQLDAQ ADRWLAKQSI AILSKETGSQ TAAIAQLQEA LVKAGLVLEV SGESHV
//
