ID A0A0M4CJI1_9CORY Unreviewed; 653 AA.
AC A0A0M4CJI1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN Name=pknB {ECO:0000313|EMBL:ALC04522.1};
GN ORFNames=CDES_00175 {ECO:0000313|EMBL:ALC04522.1};
OS Corynebacterium deserti GIMN1.010.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=931089 {ECO:0000313|EMBL:ALC04522.1, ECO:0000313|Proteomes:UP000068067};
RN [1] {ECO:0000313|EMBL:ALC04522.1, ECO:0000313|Proteomes:UP000068067}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GIMN1.010 {ECO:0000313|EMBL:ALC04522.1,
RC ECO:0000313|Proteomes:UP000068067};
RA Ruckert C., Albersmeier A., Kalinowski J.;
RT "Complete genome sequence of Corynebacterium deserti GIMN1.010 (=DSM
RT 45689), isolated from desert sand in western China.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CP009220; ALC04522.1; -; Genomic_DNA.
DR RefSeq; WP_053543739.1; NZ_CP009220.1.
DR AlphaFoldDB; A0A0M4CJI1; -.
DR STRING; 931089.CDES_00175; -.
DR KEGG; cdx:CDES_00175; -.
DR PATRIC; fig|931089.4.peg.31; -.
DR OrthoDB; 9762169at2; -.
DR Proteomes; UP000068067; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0106310; F:protein serine kinase activity; IEA:RHEA.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd06577; PASTA_pknB; 4.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 4.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR NCBIfam; NF033483; PknB_PASTA_kin; 1.
DR PANTHER; PTHR43289; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED; 1.
DR PANTHER; PTHR43289:SF32; SERINE_THREONINE-PROTEIN KINASE PKAB; 1.
DR Pfam; PF03793; PASTA; 4.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 3.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 3.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000313|EMBL:ALC04522.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:ALC04522.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 342..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..278
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 370..436
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 437..505
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 506..570
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT BINDING 38
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 653 AA; 69093 MW; F18865B6BAC0F655 CRC64;
MTFVIADRYE LGGNIGSGGM SEVFAATDTL IGREVAVKML RIDLAKDINF RERFRREAKN
SGKLSHPAIV AVFDTGEVDR DGISVPYIVM ERVHGRNLRD IVTEDGVFTP TEAARTLIPV
CEALQASHDA GIIHRDVKPA NIMITNTGGV KVMDFGIARA VDDSTSAMTQ TSAVIGTAQY
LSPEQARGKP ADARSDIYAT GCVMYELVTG KPPFEGESPF AVAYQHVQED PTPPSDFIAD
LTPTAAINVD AVILTAMAKH PADRYQTAAE MASDLGRLSR NAVSHAARAH VEAEEKEPET
LLSTRAATTV DPAAAPDARL APAAPIAAPI AAREKKRGSR GLIALTIVLA LGVVGVAGAF
TYDYLSNSST SSTHAIPNVE GFPQAEAISQ LEAAGFTVNV ATEASADIQE GLVIRTSPSV
GSEVRDGATV TITVSTGREM VNIPDVSGMT LEEAARTLED LGLVLDPSIR EEYSDTVSTG
QVIEQNPPAG QEVVVGSSVS LTVSSGVENI RVPTATGMNW SQAEQNLTSL GFTPSVTYVD
SEHPEGEVLT VSNEGTEMPK GSVITVEVSN GMLINAPDLA RLNQQQAIDA LRAAGWTAPD
QSLIVGEPIA TVALVDQGRI GFQSPSANAL FRKDAQVTVR FFEFNIEALV QNP
//
