ID A0A0M4D0J6_SPHS1 Unreviewed; 527 AA.
AC A0A0M4D0J6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA ligase (ATP) {ECO:0000256|ARBA:ARBA00012727};
DE EC=6.5.1.1 {ECO:0000256|ARBA:ARBA00012727};
GN ORFNames=LH20_15425 {ECO:0000313|EMBL:ALC13347.1};
OS Sphingopyxis sp. (strain 113P3).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=292913 {ECO:0000313|EMBL:ALC13347.1, ECO:0000313|Proteomes:UP000061305};
RN [1] {ECO:0000313|EMBL:ALC13347.1, ECO:0000313|Proteomes:UP000061305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=113P3 {ECO:0000313|EMBL:ALC13347.1,
RC ECO:0000313|Proteomes:UP000061305};
RX PubMed=26472829;
RA Ohtsubo Y., Nagata Y., Numata M., Tsuchikane K., Hosoyama A., Yamazoe A.,
RA Tsuda M., Fujita N., Kawai F.;
RT "Complete Genome Sequence of Polyvinyl Alcohol-Degrading Strain
RT Sphingopyxis sp. 113P3 (NBRC 111507).";
RL Genome Announc. 3:e01169-15(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + (deoxyribonucleotide)n-3'-hydroxyl + 5'-phospho-
CC (deoxyribonucleotide)m = (deoxyribonucleotide)n+m + AMP +
CC diphosphate.; EC=6.5.1.1; Evidence={ECO:0000256|ARBA:ARBA00034003};
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DR EMBL; CP009452; ALC13347.1; -; Genomic_DNA.
DR RefSeq; WP_053554943.1; NZ_CP009452.1.
DR AlphaFoldDB; A0A0M4D0J6; -.
DR STRING; 292913.LH20_15425; -.
DR KEGG; sphp:LH20_15425; -.
DR PATRIC; fig|292913.6.peg.3130; -.
DR OrthoDB; 9767858at2; -.
DR Proteomes; UP000061305; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd07897; Adenylation_DNA_ligase_Bac1; 1.
DR CDD; cd07972; OBF_DNA_ligase_Arch_LigB; 1.
DR Gene3D; 1.10.3260.10; DNA ligase, ATP-dependent, N-terminal domain; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR026333; ATP_dep_DNA_lig_pp_1105_fam.
DR InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR InterPro; IPR036599; DNA_ligase_N_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR NCBIfam; TIGR04120; DNA_lig_bact; 1.
DR PANTHER; PTHR45674; DNA LIGASE 1/3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45674:SF13; DNA LIGASE-RELATED; 1.
DR Pfam; PF04679; DNA_ligase_A_C; 1.
DR Pfam; PF01068; DNA_ligase_A_M; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ALC13347.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000061305}.
FT DOMAIN 303..433
FT /note="ATP-dependent DNA ligase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50160"
SQ SEQUENCE 527 AA; 58364 MW; 13E4013F7A127031 CRC64;
MKRFAALIDR LVYTRSRNSK LALIVDYVRH TPDPDRGWAL AALTDALDFP AVKAGTVRAL
LGARVDEELF RLSRHFVGDT AETAALLWPE AALGKEAEEL SVAQAVDALS RATRGDAPAI
LTSLLDRLDG DGRYALLKLA LGGMRVGVSA RLAKQAFAQA FDVSIDDVEE LWHAIPPPYT
TLFAWGEGKA PRPDLTDVAF FRPFMLAHPL EGESIDLSDF AAEWKWDGIR VQLVHGGGET
RIYSRGGEEI GGAFPELLAA FDQDAVIDGE LLVRGEAQGG AEGGAASFNA LQQRLGRKTV
TRKMLADYPA FVRVYDLIAV DGADLRALPW HERRRQLEGF VPRLAASHFD LSPVIEAAHF
EELATLRAGA RDAAIEGVML KRRDAPYIAG RRAGLWYKWK RDPLVADCVM MYAQRGNGRR
ASFYSDYTFG CWTDAGELLP VGKAYSGFTD EELKWLDKFV RDHTIGRFGP VREVEKTLVL
EVAFDSIHAS KRHKSGLAMR FPRISRIRRD KPAEEADRIA TLRAMAT
//
