ID   A0A0M4E6Y4_DROBS        Unreviewed;       901 AA.
AC   A0A0M4E6Y4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=CG18659 {ECO:0000313|EMBL:ALC42354.1};
GN   ORFNames=Dbus_chr2Rg1933 {ECO:0000313|EMBL:ALC42354.1};
OS   Drosophila busckii (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC42354.1, ECO:0000313|Proteomes:UP000494163};
RN   [1] {ECO:0000313|EMBL:ALC42354.1, ECO:0000313|Proteomes:UP000494163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole larvae {ECO:0000313|EMBL:ALC42354.1};
RA   Zhou Q., Bachtrog D.;
RT   "Ancestral chromatin configuration constrains chromatin evolution on
RT   differentiating sex chromosomes in Drosophila.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP012524; ALC42354.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M4E6Y4; -.
DR   SMR; A0A0M4E6Y4; -.
DR   STRING; 30019.A0A0M4E6Y4; -.
DR   OMA; KTNTAMV; -.
DR   Proteomes; UP000494163; Chromosome 2r sequence.
DR   GO; GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   Gene3D; 3.30.450.200; -; 1.
DR   Gene3D; 3.40.50.11500; -; 1.
DR   Gene3D; 6.10.140.1000; -; 1.
DR   InterPro; IPR001194; cDENN_dom.
DR   InterPro; IPR005112; dDENN_dom.
DR   InterPro; IPR043153; DENN_C.
DR   InterPro; IPR040032; DENND1A/B/C.
DR   InterPro; IPR037516; Tripartite_DENN.
DR   InterPro; IPR005113; uDENN_dom.
DR   PANTHER; PTHR13196; DENN DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR13196:SF14; UDENN DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03455; dDENN; 1.
DR   Pfam; PF02141; DENN; 1.
DR   Pfam; PF03456; uDENN; 1.
DR   SMART; SM00801; dDENN; 1.
DR   SMART; SM00799; DENN; 1.
DR   SMART; SM00800; uDENN; 1.
DR   PROSITE; PS50211; DENN; 1.
PE   4: Predicted;
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Reference proteome {ECO:0000313|Proteomes:UP000494163}.
FT   DOMAIN          24..387
FT                   /note="UDENN"
FT                   /evidence="ECO:0000259|PROSITE:PS50211"
FT   REGION          435..505
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          573..660
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          723..769
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..480
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        578..601
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..647
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        743..757
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   901 AA;  99450 MW;  E5E210F61BDD0B79 CRC64;
     MGSRIKNDVK KLFEFWCEVQ PSHGIERGTI GRNSRGASTP AGVIIESFPE GFRDKEVLTG
     IPSFAFPCEL DRRSVQSYSF VHTTGDSKWR FGFCRHDPKT DTAMVLITYL PWHDIFLKLL
     IVLAELRRTD PQGFRAFLAE AYNRGVPESG GSLTVFYNSG QNHFTFERPL QFMLPSIPEN
     HNLNLYYNFV DPKEMISVFA AMLAERRIIF TSSHLDRLSS CIQAAHAFLY PMVWQHIFIP
     VLPWEFKDYL GAPMPYLIGV PKPVLDAVSA DELGEVVILN CDTKLFESPF EDVRALPSEI
     VSQLKKNLSH TQDHIGDRVS KIFLGALVQL IGGYRDAVEF HDTSKSFNHA KFIESRPVHL
     HAFLAKMMEL QIFAQFIDER LKMLNSGLGF SDEFELETVR YAEKLKKRGR NYVFLKHVKD
     KVKEGSRGVK TAYKKWRDNG SHNPSHQFHF GLGSPQHSDR PDGNQTAYGR KATHHSAPSS
     PVCSKRLEHN GRLGGAAGKE QVEPSRRTAV PLAMSSSSSH IQPHGYALGA TLTAGNHHAV
     GASPAISSAS SLCSSSEMNL SQELQNHPLF KTPAVDRSQL KPQANNIDTP SRSTRLPASY
     YNHPFASQAH PQVDGKPPPS LSRQLNSSTP QKSRLFTSND SSFDSPPDVQ SPPVPPRRQC
     SANAVVAATA AAVSAGINRL ERNCWQDEQH SDMVRSSNSS ESSSSYSSGA SFVTAASRFS
     QLNVSSPGSE GAPIPLPRAK RESPRSSSAS SSLAPPKAED SMNDLISLDD SNNTSFDLED
     FDPLNQNARP LPPPNKFFNG NKSKSSTLPV GINSSVVASQ ANNSVNNPLY PFFAPKHMAT
     VAAVTGQRIN ALPSPIPHSN KLVVKPDDDF ELLRKYGLDQ FTLNANGTDV GKGMNNWTTF
     D
//