ID   A0A0M4E9K0_DROBS        Unreviewed;       846 AA.
AC   A0A0M4E9K0;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Muskelin {ECO:0000313|EMBL:ALC41608.1};
DE   Flags: Fragment;
GN   ORFNames=Dbus_chr2Rg1187 {ECO:0000313|EMBL:ALC41608.1};
OS   Drosophila busckii (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC41608.1, ECO:0000313|Proteomes:UP000494163};
RN   [1] {ECO:0000313|EMBL:ALC41608.1, ECO:0000313|Proteomes:UP000494163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole larvae {ECO:0000313|EMBL:ALC41608.1};
RA   Zhou Q., Bachtrog D.;
RT   "Ancestral chromatin configuration constrains chromatin evolution on
RT   differentiating sex chromosomes in Drosophila.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP012524; ALC41608.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M4E9K0; -.
DR   STRING; 30019.A0A0M4E9K0; -.
DR   OMA; NKQDYKH; -.
DR   Proteomes; UP000494163; Chromosome 2r sequence.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006594; LisH.
DR   InterPro; IPR010565; Muskelin_N.
DR   PANTHER; PTHR15526; MUSKELIN; 1.
DR   PANTHER; PTHR15526:SF5; MUSKELIN; 1.
DR   Pfam; PF13415; Kelch_3; 1.
DR   Pfam; PF06588; Muskelin_N; 1.
DR   SMART; SM00667; LisH; 1.
DR   SUPFAM; SSF50965; Galactose oxidase, central domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS50896; LISH; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Reference proteome {ECO:0000313|Proteomes:UP000494163};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          40..234
FT                   /note="Muskelin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06588"
FT   REGION          739..810
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        779..803
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ALC41608.1"
SQ   SEQUENCE   846 AA;  97074 MW;  E89C31E335D3F237 CRC64;
     ASTTTTSSPT DSSANGSYSA APVAAVTNTN TQKASFTLFE KLSFSIFRYS SYSPNYLPEN
     VLVDCPNDQT SRWSAYTNSP PQYLTLKLKR PAIVKKIKFG KFEKSHVCNI KKFRVFGGLE
     DEHMVLLLEG GLKNDNIPEV FNLRCMTEDG TENLPILYLK IVPLLSWGPS FNFSIWYIEL
     HGQDDPMYTC ARMKSYNSLR EVEIIKLCLK HFRQQGYMKA FDALQEQTQV RLEHTLISEL
     HKYLVVDGDF EGAERFIADC IDEGLMDDYL NKKDYKHTWQ IKYTLSDVKP GNRGGHQLVV
     DAKKRLIYLY GGWDGYQDLS DLWLYNIELD EWTLLCERSE LVNGPTPRSC HKMIFDPVSE
     NIFMLGRYLD NSIRTSEYIK SDFYLYDTRA RIWMQICDDT SQVGGPQLVY DHQMCMDTDK
     RTIYVFGGKI LTPRSSTATS AIEAEYSGLF SYHIATNTWT QILVDCHHAS ASQADVMSIK
     SRITHCMVFH TKQRKLYIYG GQRGKEDLDE LLTYDVDTQA ISILNKEHSH QCSTASTEAK
     FEPSPGYTLR ATIDCDRDEI YVFSSLHKIK DRRDVHHIDA SNSFWVYSLR TYKWSRIYYR
     RHSAQDVSSI YKANFLGASK GDGALEPCPR YAHQLVYDEV AKTHYLFGGN PGISQYQQLR
     LDDFWMLYLE KPKREEILNH CRYLIRKLHY EEMTGTEPLK AMQYLRKQIS AVIDHNDDEQ
     LNNFHKLAAL LFKSDDNDAS DVQSLTTTPL REKAEEINEN AIETPNAEDT HLGSDDGKLE
     SNESLTTSGI SETASTPNDS SCTKRARTDA KGELQNHRAF LFNKLVQLMP SGMVQPERNL
     SDFVVI
//