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Database: UniProt
Entry: A0A0M4ECP2_DROBS
LinkDB: A0A0M4ECP2_DROBS
Original site: A0A0M4ECP2_DROBS 
ID   A0A0M4ECP2_DROBS        Unreviewed;       146 AA.
AC   A0A0M4ECP2;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   05-JUN-2019, entry version 14.
DE   RecName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   AltName: Full=Mediator complex subunit 9 {ECO:0000256|RuleBase:RU364145};
DE   Flags: Fragment;
GN   Name=MED9 {ECO:0000256|RuleBase:RU364145};
GN   ORFNames=Dbus_chr2Rg155 {ECO:0000313|EMBL:ALC40576.1};
OS   Drosophila busckii (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Ephydroidea; Drosophilidae; Drosophila.
OX   NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC40576.1, ECO:0000313|Proteomes:UP000092553};
RN   [1] {ECO:0000313|EMBL:ALC40576.1, ECO:0000313|Proteomes:UP000092553}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole larvae {ECO:0000313|EMBL:ALC40576.1};
RA   Zhou Q., Bachtrog D.;
RT   "Ancestral chromatin configuration constrains chromatin evolution on
RT   differentiating sex chromosomes in Drosophila.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the Mediator complex, a coactivator
CC       involved in the regulated transcription of nearly all RNA
CC       polymerase II-dependent genes. Mediator functions as a bridge to
CC       convey information from gene-specific regulatory proteins to the
CC       basal RNA polymerase II transcription machinery. Mediator is
CC       recruited to promoters by direct interactions with regulatory
CC       proteins and serves as a scaffold for the assembly of a functional
CC       preinitiation complex with RNA polymerase II and the general
CC       transcription factors. {ECO:0000256|RuleBase:RU364145}.
CC   -!- SUBUNIT: Component of the Mediator complex.
CC       {ECO:0000256|RuleBase:RU364145, ECO:0000256|SAAS:SAAS00869477}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364145,
CC       ECO:0000256|SAAS:SAAS00869478}.
CC   -!- SIMILARITY: Belongs to the Mediator complex subunit 9 family.
CC       {ECO:0000256|RuleBase:RU364145}.
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DR   EMBL; CP012524; ALC40576.1; -; Genomic_DNA.
DR   Proteomes; UP000092553; Chromosome 2r sequence.
DR   GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   InterPro; IPR037212; Med7/Med21-like.
DR   InterPro; IPR011425; Med9.
DR   InterPro; IPR039242; MED9_metazoa.
DR   PANTHER; PTHR20844; PTHR20844; 1.
DR   Pfam; PF07544; Med9; 1.
DR   SUPFAM; SSF140718; SSF140718; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|RuleBase:RU364145};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000092553};
KW   Nucleus {ECO:0000256|RuleBase:RU364145,
KW   ECO:0000256|SAAS:SAAS00869474};
KW   Reference proteome {ECO:0000313|Proteomes:UP000092553};
KW   Transcription {ECO:0000256|RuleBase:RU364145,
KW   ECO:0000256|SAAS:SAAS00869482};
KW   Transcription regulation {ECO:0000256|RuleBase:RU364145,
KW   ECO:0000256|SAAS:SAAS00869473}.
FT   REGION        1     51       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0M4ECP2}.
FT   COILED      117    144       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS      9     47       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0M4ECP2}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:ALC40576.1}.
SQ   SEQUENCE   146 AA;  16579 MW;  5D250FBC95B7BEC2 CRC64;
     IMELSPSQID RKPTLTADGL VQTSNSPFEP TTTSAETQTS NGGGGVNTGG PLTVDQIDVE
     ILPLIYDIVR SVEKDPLENA VKLRESQDCN HKILQLQKRF ESAREQIRQL PGIDYNKEEQ
     QQRLELLRSQ LKLKQQLIRK YKDTEF
//
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