ID A0A0M4EEM1_DROBS Unreviewed; 217 AA.
AC A0A0M4EEM1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=Npc2c {ECO:0000313|EMBL:ALC46466.1};
GN ORFNames=Dbus_chr3Rg1216 {ECO:0000313|EMBL:ALC46466.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC46466.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC46466.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC46466.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NPC2 family.
CC {ECO:0000256|ARBA:ARBA00006370}.
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DR EMBL; CP012526; ALC46466.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M4EEM1; -.
DR SMR; A0A0M4EEM1; -.
DR STRING; 30019.A0A0M4EEM1; -.
DR OMA; QCKNKPF; -.
DR Proteomes; UP000494163; Chromosome 3r sequence.
DR GO; GO:0032934; F:sterol binding; IEA:InterPro.
DR GO; GO:0015918; P:sterol transport; IEA:InterPro.
DR Gene3D; 2.60.40.770; -; 1.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR003172; ML_dom.
DR InterPro; IPR039670; NPC2-like.
DR PANTHER; PTHR11306; NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED; 1.
DR PANTHER; PTHR11306:SF36; NIEMANN-PICK TYPE C-2C-RELATED; 1.
DR Pfam; PF02221; E1_DerP2_DerF2; 1.
DR SMART; SM00737; ML; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000494163}.
FT DOMAIN 73..199
FT /note="MD-2-related lipid-recognition"
FT /evidence="ECO:0000259|SMART:SM00737"
SQ SEQUENCE 217 AA; 24512 MW; 6B1BB88FFCFA4326 CRC64;
MLDISHIQHF GHHGKAFCYL MLNRCDNSFI HSFKFQTFSC FLGNLSEQIR TKMLRFVLLT
LACLCVAEGV TNFKQCKGKP APLKVNVHDC EEPPCVVYKG QFALMDVQFV GNENNSRDLE
TKVTAKVFGI TVPYDLPKEV SDICENLLYG AMCPIDKGED VTYRFRFYVE QEFPEITTEV
TVTLNDANME PVACFIVSCK IRKGPASRNA TDTLLLA
//
