ID A0A0M4EFD9_DROBS Unreviewed; 741 AA.
AC A0A0M4EFD9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Mad1 {ECO:0000313|EMBL:ALC42038.1};
GN ORFNames=Dbus_chr2Rg1617 {ECO:0000313|EMBL:ALC42038.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC42038.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC42038.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC42038.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MAD1 family.
CC {ECO:0000256|ARBA:ARBA00008029}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP012524; ALC42038.1; -; Genomic_DNA.
DR RefSeq; XP_017839123.1; XM_017983634.1.
DR AlphaFoldDB; A0A0M4EFD9; -.
DR SMR; A0A0M4EFD9; -.
DR STRING; 30019.A0A0M4EFD9; -.
DR GeneID; 108597198; -.
DR OMA; YKLDFMP; -.
DR OrthoDB; 8224at2759; -.
DR Proteomes; UP000494163; Chromosome 2r sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 3.30.457.60; -; 1.
DR Gene3D; 6.10.250.90; -; 1.
DR InterPro; IPR008672; Mad1.
DR PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR Pfam; PF05557; MAD; 1.
DR SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000494163}.
FT REGION 596..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 83..265
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 388..422
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 741 AA; 86012 MW; B35A4A8BF4587848 CRC64;
MDEIRSSLDN IMARFNDSIV NSAPKRLSFD RLSMSFSEDS STMTVPKKRR LEEYNESSLS
ASLNASSTSL SNSFNDPNGP WELRKLRAEL IESKAVVAEL QDRLKHQDKE YRSEIALEES
KSAALKQQCD FTSAKMLELE RQVQLLRKRE HAARQETTQA IADLAAQKLK YEATISRLKQ
QQQQAEQDAI ELQSALSNEI SEYKRSSERS ELELDACQGE LDRIRERYED CKQQAADFEK
LSQRYELQQQ QLETSEARIK ELEYQIASYT DWEQVTKQTQ ARLLSLPELQ TEVTRLKAQN
KQLHTLIGNK LLLEEQVHDY KTRLQREEGA RAEAATLQVK LTHVEQELRE WVQLAQDHCL
PNTLVSPMAL RTRIEQLLQA DIVRVAEQSS ASADVKQLQS ALRELEQKCS VYLKNIEDMN
VVLKRHKSFR ERLQRKLLIV CKERDFYKQL LDNFDKDMTM SNASNVDMTV DMQLRYRNEV
LERTVTGYKE MCSTLERELQ AMRQQEQLQD PSPSTECGYD SVKQELDTLR MENERLTRRK
EELELELEHR CLRGDFNMGQ YKVLHIKQNP AQEAYDISKN IVEKLQAEIE RLKRRNKKLE
EDQEQTQDTI SGSTGMTMNF KELNQMRAEL ETANGKMKKM KDCFKAASKE FRDVCYMLLG
YRIDRVGANS HYRISSMYAE SPDDYLSISV NESNCLALLE SPYSKTLKPA IDQQLAANNS
FPAFFSALTL ELFQRATVTI T
//
