ID A0A0M4ERA0_DROBS Unreviewed; 1044 AA.
AC A0A0M4ERA0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Snz {ECO:0000313|EMBL:ALC48615.1};
DE Flags: Fragment;
GN ORFNames=Dbus_chrXg471 {ECO:0000313|EMBL:ALC48615.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC48615.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC48615.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC48615.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; CP012528; ALC48615.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M4ERA0; -.
DR SMR; A0A0M4ERA0; -.
DR STRING; 30019.A0A0M4ERA0; -.
DR OMA; LYALMGE; -.
DR Proteomes; UP000494163; Chromosome x sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06878; PX_SNX25; 1.
DR CDD; cd08720; RGS_SNX25; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR037899; SNX25_PX.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775:SF48; FI21262P1; 1.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000494163};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..295
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 407..522
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 671..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 576..624
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1044
FT /evidence="ECO:0000313|EMBL:ALC48615.1"
SQ SEQUENCE 1044 AA; 118426 MW; 0ADF45F7E148D883 CRC64;
MEQRLPLFPI EPEPPATPTQ RLTLLATRCL RALQLNWKII VSSSTLTLLA VCWYYPTFFL
FFAFVIYSLL LVFAAVAGTV YIYYIFTTNE PSKPNRLPSK LLYNATKSQI FDLPNPIKNP
SNLPLVFGKT VDLQLQQIIE YVLRDFMVPW LGYVVTKPKL INDVVREDLW NAIQKIHERA
IKMDPAKIIA VDMVNRVTVH LEKIRIAEAR AAETNSPPVF SSNSYLVDEQ QEMEFLRKLC
EIMIILLLPR GYSLPPLKVL LSELLSFKIF FPMIKMLTSP DYINQKVVQN IETRLAAAAI
SKRSYEYAAS FEEFLKIINN SGNLEELSLI RKSIVNDLMH ATSMQNLQRA KGLDPDTEDH
TLSKSELTAA VRLKRYVQQL SVAKNQCEKN LAKFGWNGNY SSDTDLTLLE ILNTAVGRRY
FTLFLEPLKA SALVGFYLAV EEMKHAPKSS THQLGTEIFY CYIRVPKPEI QIDKHERKLI
ETFVLGDAGP EIFYDMQRNI LRTLEDKYYP PFVLSEQYRQ LKEALDSNEF NDPTLLMCPE
TPDDEQAMVA EALNGAGMPV AAIDVAAHTS YARRKLEQIQ ERIDKKNQAL DALKYSVKPE
SKVLQILEKE MEWLKSEKRQ TEAHLRRTDA WTEHLGKWKA TIQSVEVSDE KESLQFMILV
HVDEDINAPA GQATTAKSGD SSSSHHKLQR RRPSGISSGW VVLRSLNQVH ELQRKLRHVS
SNLKSLDLPT NFKFFFLKTD RHAQEKAKAQ IQKFLNFILE DDHLNGSEAI YTFLSPSSDH
LKQTLPSPKK SKFSLSTLFK SDAAKAHESS KATDPFWGLQ RDEDDMSTYL EGESSSDVKL
LADLDSKDSI AEPLYALMGE IFDMGGVFKW LRKSIISFVQ ITYGRTINRQ IRESVASLFE
ESMLHNYFSA ILKSFWPGGV LASAYPVRSD DMKEMTTNAA KALITDHIPE VLCSLVGAQA
AKRGVMKVFE ALQNPLYNKQ LFYELLEILM VEFFPEIRQL RVNNANGSKL NTTSSGVAAV
SAAAAALAAV TALPTLNSHH QSQQ
//
