ID A0A0M4ES12_DROBS Unreviewed; 307 AA.
AC A0A0M4ES12;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 03-MAY-2023, entry version 22.
DE SubName: Full=CG1542 {ECO:0000313|EMBL:ALC48038.1};
GN ORFNames=Dbus_chr3Rg2788 {ECO:0000313|EMBL:ALC48038.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC48038.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC48038.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC48038.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the processing of the 27S pre-rRNA.
CC {ECO:0000256|ARBA:ARBA00003387}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the EBP2 family.
CC {ECO:0000256|ARBA:ARBA00007336}.
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DR EMBL; CP012526; ALC48038.1; -; Genomic_DNA.
DR RefSeq; XP_017848201.1; XM_017992712.1.
DR AlphaFoldDB; A0A0M4ES12; -.
DR STRING; 30019.A0A0M4ES12; -.
DR GeneID; 108603690; -.
DR OMA; RETMFHR; -.
DR OrthoDB; 11782at2759; -.
DR Proteomes; UP000494163; Chromosome 3r sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR008610; Ebp2.
DR PANTHER; PTHR13028; RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR13028:SF0; RRNA-PROCESSING PROTEIN EBP2-RELATED; 1.
DR Pfam; PF05890; Ebp2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000494163};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..263
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..307
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 307 AA; 35376 MW; 41B39B4A7DF26D74 CRC64;
MSDFEMEESG SEYDSGDNSD AELQAAFERG DLKPGLNVEF NGERDKINDI TKLLAKTQAI
RLQLPWLERL DMVNNLAPLA PELAVQLEKH EQKRANQFKG NAKIPYISPD EDPVLNDFKR
EMMFHRQAQC AVIEGIRQLH ELGIKTRRPD DYFAEMAKTD EHMQKVRANL MAKQQGQAKS
ERIKQIREQR KMGKMLAKQT KVQREAEKKE MLDKLKKFRK GKLKNLDFLE DAKALESKQK
QSVDKRKQRN KKFGFGGKKK GLKRNTKSSA DGLESEKSTR RQRGVKAGAS VNKRMGKSRR
MKAKARK
//
