ID   A0A0M4F376_DROBS        Unreviewed;       862 AA.
AC   A0A0M4F376;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Atx2 {ECO:0000313|EMBL:ALC46012.1};
GN   ORFNames=Dbus_chr3Rg762 {ECO:0000313|EMBL:ALC46012.1};
OS   Drosophila busckii (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC46012.1, ECO:0000313|Proteomes:UP000494163};
RN   [1] {ECO:0000313|EMBL:ALC46012.1, ECO:0000313|Proteomes:UP000494163}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole larvae {ECO:0000313|EMBL:ALC46012.1};
RA   Zhou Q., Bachtrog D.;
RT   "Ancestral chromatin configuration constrains chromatin evolution on
RT   differentiating sex chromosomes in Drosophila.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ataxin-2 family.
CC       {ECO:0000256|ARBA:ARBA00007503}.
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DR   EMBL; CP012526; ALC46012.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M4F376; -.
DR   STRING; 30019.A0A0M4F376; -.
DR   OMA; MRVYQDQ; -.
DR   Proteomes; UP000494163; Chromosome 3r sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   CDD; cd00600; Sm_like; 1.
DR   InterPro; IPR045117; ATXN2-like.
DR   InterPro; IPR009604; LsmAD_domain.
DR   InterPro; IPR047575; Sm.
DR   InterPro; IPR025852; SM_dom_ATX.
DR   PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR   PANTHER; PTHR12854:SF7; ATAXIN-2 HOMOLOG; 1.
DR   Pfam; PF06741; LsmAD; 1.
DR   Pfam; PF14438; SM-ATX; 1.
DR   SMART; SM01272; LsmAD; 1.
DR   PROSITE; PS52002; SM; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000494163}.
FT   DOMAIN          70..146
FT                   /note="Sm"
FT                   /evidence="ECO:0000259|PROSITE:PS52002"
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          405..539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          554..587
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..679
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          694..727
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          780..816
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..47
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        277..324
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        337..377
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..524
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        565..587
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        604..637
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        649..668
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        785..809
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   862 AA;  91387 MW;  BD02418536798298 CRC64;
     MNNNSKRKTR PSGGGGGGGG ASGGISRYNS NDNNSLRPSN NKGGLGSAGA NSGAAGVGRT
     LAQGVYNNTY FMHSATSLVG SVVEVRLRSG NVYEGVFRTF SGNFDIALEL PACIKAKNQP
     DEAKTVPKHI IFPADTVVTI MAKDFDSNYA TVGAFQTDGA ISDKCNGSRF DEKELEPWDA
     GANGDIDIEL DGAANGWDAN EMFRKNENVF GVTSTFDDSL SSYTVALDKG DSLEYKEAEA
     KAEKLAAEIE NNPTCRERLD LENGDEESLF AAVERPTPEQ DMERDRERER DRDREREREE
     RERERERERE RERDRDRDRG NKPRGNGGGD YQLRETMSSD RYITKQPRNN NNNGPPSSHP
     GLSSQSSRDN RDSIMMGQGQ QGGGGGAPQS AAVLLLAGSL KNTNMSAPGA GPVADNKYGN
     NGGPMIKRKT VPPAGKIMRD NRNPNSVGVG AGNSSNVPQP NNANNGAGKG SGGYQSSMGM
     QNQYSYQPNS QLMHGSSGYR QQGHLGGTSK LNGNDANSNA GKPLPQRQMP PGVQQPQTSP
     VVISSPVILD QPPPPVAVAS TVKPDATPAT GSVISSSTTP TGIASTPTTV TTGAAAVAAA
     ASTEKTTPAA TATSAATGSS TTTTTTAGTT GTTPVVKKHV LNPSAKPFTP RGPSTPNPSR
     PHTPQTPVPL PGIYTTTGAH MPAANQPIYM MPQPHAFQAP THPGGQAPRM RRSYAPMGSS
     QVHVSASAAT GPPLMATTPI QQFIQYPHTP HPQHFQSPAY APMPMRVYSD QTQQLQFLAQ
     TPPSTTPSPG QPHQAFHPPP QPSPAGGGPQ PAAFTPQTQP QAYQFMCVHP NIIPNPYFPG
     ATPQHPPQNQ QYHLVMQPHT TQ
//