ID   A0A0M4GUF6_9GAMM        Unreviewed;       369 AA.
AC   A0A0M4GUF6;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Muconate cycloisomerase {ECO:0000313|EMBL:ALD00994.1};
GN   ORFNames=AMQ28_00630 {ECO:0000313|EMBL:ALD00994.1}, H0S58_05890
GN   {ECO:0000313|EMBL:QPF39016.1};
OS   Acinetobacter sp. TTH0-4.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC   Acinetobacter.
OX   NCBI_TaxID=1646498 {ECO:0000313|EMBL:ALD00994.1, ECO:0000313|Proteomes:UP000055186};
RN   [1] {ECO:0000313|EMBL:ALD00994.1, ECO:0000313|Proteomes:UP000055186}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TTH0-4 {ECO:0000313|EMBL:ALD00994.1,
RC   ECO:0000313|Proteomes:UP000055186};
RA   Zhang G.;
RT   "Acinetobacter qinghaiensis sp. nov., isolated from active layer of
RT   permafrost region.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QPF39016.1, ECO:0000313|Proteomes:UP000594614}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1BD1 {ECO:0000313|EMBL:QPF39016.1,
RC   ECO:0000313|Proteomes:UP000594614};
RA   Ghaly T.M., Sajjad A., Tetu S.G., Gillings M.R.;
RT   "A family of multi-drug resistance mega-plasmids in Acinetobacter
RT   species.";
RL   Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- PATHWAY: Aromatic compound metabolism. {ECO:0000256|ARBA:ARBA00005211}.
CC   -!- SIMILARITY: Belongs to the mandelate racemase/muconate lactonizing
CC       enzyme family. {ECO:0000256|ARBA:ARBA00008031}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP012608; ALD00994.1; -; Genomic_DNA.
DR   EMBL; CP059079; QPF39016.1; -; Genomic_DNA.
DR   RefSeq; WP_053577890.1; NZ_CP059079.1.
DR   AlphaFoldDB; A0A0M4GUF6; -.
DR   STRING; 1646498.AMQ28_00630; -.
DR   KEGG; att:AMQ28_00630; -.
DR   PATRIC; fig|1646498.3.peg.127; -.
DR   Proteomes; UP000055186; Chromosome.
DR   Proteomes; UP000594614; Chromosome.
DR   GO; GO:0018850; F:chloromuconate cycloisomerase activity; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0018849; F:muconate cycloisomerase activity; IEA:InterPro.
DR   GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd03318; MLE; 1.
DR   Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR   Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR   InterPro; IPR013370; Chloromuconate_cycloisomerase.
DR   InterPro; IPR036849; Enolase-like_C_sf.
DR   InterPro; IPR029017; Enolase-like_N.
DR   InterPro; IPR029065; Enolase_C-like.
DR   InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR   InterPro; IPR013342; Mandelate_racemase_C.
DR   InterPro; IPR013341; Mandelate_racemase_N_dom.
DR   NCBIfam; TIGR02534; mucon_cyclo; 1.
DR   PANTHER; PTHR48073:SF2; O-SUCCINYLBENZOATE SYNTHASE; 1.
DR   PANTHER; PTHR48073; O-SUCCINYLBENZOATE SYNTHASE-RELATED; 1.
DR   Pfam; PF13378; MR_MLE_C; 1.
DR   Pfam; PF02746; MR_MLE_N; 1.
DR   SFLD; SFLDG01258; (chloro)muconate_cycloisomeras; 1.
DR   SFLD; SFLDG00180; muconate_cycloisomerase; 1.
DR   SFLD; SFLDF00009; o-succinylbenzoate_synthase; 1.
DR   SMART; SM00922; MR_MLE; 1.
DR   SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR   SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR   PROSITE; PS00909; MR_MLE_2; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ALD00994.1};
KW   Manganese {ECO:0000256|ARBA:ARBA00023211}.
FT   DOMAIN          144..241
FT                   /note="Mandelate racemase/muconate lactonizing enzyme C-
FT                   terminal"
FT                   /evidence="ECO:0000259|SMART:SM00922"
SQ   SEQUENCE   369 AA;  40135 MW;  72DA3C0A4481F1C0 CRC64;
     MYKSIETLLV EIPTIRPHKM AVATMQTQTL VLIKIVTEDG FTGWGEATTI GGLGYGDESP
     ESVKTNIETY FAPLLKSLSG LSFAQTIQTI KRNINGNRFA KCAIQTALLD IQAQRLGLPL
     SEVLGGRLRN SVPVLWVLAS GDTDKDIAEA KKMIELKRHN VFKLKIGSRP VEDDVAHVLA
     IKKALGSDIS IRVDVNRAWT ELQAIKGIQL LQDGGVDLIE QPCAIENLDA MQRLTRRFDI
     AIMADESLYG PQSAYQIARN NGASVFAVKV AQSGGLIEGC EVGKIAKLAG IDLYGGTMLE
     GPVGTIASAH VFSTFESLAY GTELFGPLLL TEDILTTPLQ YQNYELVLPT VPGLGIELDL
     NKIDNLRRQ
//