ID A0A0M4Q4A7_9PSEU Unreviewed; 490 AA.
AC A0A0M4Q4A7;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=FAD-containing monooxygenase EthA {ECO:0000313|EMBL:ALE85454.1};
GN ORFNames=XF36_21800 {ECO:0000313|EMBL:ALE85454.1};
OS Pseudonocardia sp. HH130629-09.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Pseudonocardia.
OX NCBI_TaxID=1641402 {ECO:0000313|EMBL:ALE85454.1, ECO:0000313|Proteomes:UP000062082};
RN [1] {ECO:0000313|EMBL:ALE85454.1, ECO:0000313|Proteomes:UP000062082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HH130629-09 {ECO:0000313|EMBL:ALE85454.1,
RC ECO:0000313|Proteomes:UP000062082};
RX PubMed=26438860; DOI=10.1073/pnas.1515348112;
RA Sit C.S., Van Arnam E.B., Ramadhar T.R.;
RT "Variable genetic architectures produce virtually identical molecules in
RT bacterial symbionts of fungus-growing ants.";
RL Proc. Natl. Acad. Sci. U.S.A. 112:13150-13154(2015).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-binding monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00010139}.
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DR EMBL; CP011868; ALE85454.1; -; Genomic_DNA.
DR RefSeq; WP_060713403.1; NZ_CP011868.1.
DR AlphaFoldDB; A0A0M4Q4A7; -.
DR KEGG; pseh:XF36_21800; -.
DR PATRIC; fig|1641402.3.peg.4668; -.
DR OrthoDB; 5168853at2; -.
DR Proteomes; UP000062082; Chromosome.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0047091; F:L-lysine 6-monooxygenase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR43872; MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED; 1.
DR PANTHER; PTHR43872:SF1; MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED; 1.
DR Pfam; PF00743; FMO-like; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:ALE85454.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000062082}.
SQ SEQUENCE 490 AA; 55093 MW; 00B4B492865595C9 CRC64;
MTATTSEHVD VLIVGAGVSG IGAAHRLREE FPDRSFVLLE AQDAPGGTWW THRFPGARSD
SDLFTYGYRH KPWTGPSIAA GAEILAYLDE VIAEDDLAGH IRYHHRVTAL SWSSAEYRWT
AEVTRTDTGE TLSTTASFLW MCQGYYNHDE PYTPQWPGLE QYAGTVVHPQ SWPSDLDVTG
AKVLVIGSGA TAATVVPATA ATAEHVTMLQ RSPSYWFPAP TVHDLATMLE PLDLPAEWTH
EILRRTYVQQ LDWLATTGRD DPDALHEFLI ESIRPLLPEG TDIEKHFVPR YRPWQQRIAF
VPDGDFFAAM REGKASVVTD TIARFTEKGV ELDSGEVIEA DVVVTATGFD LAVFGDIPFT
VDGEPVDFTR HVTWRGLMIE GIPNMAYAFG YFRHSWTLRI DLVNDLIGRI LARMDERRHQ
VVVPTVAPQD ADMPRLPWVS EENFNPGYIG RSAHRMFGQG DREPWTHMHE HDVDRVELPK
ADLDDGLQYR
//
