ID A0A0M5ILC1_SPHS1 Unreviewed; 479 AA.
AC A0A0M5ILC1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Dioxygenase {ECO:0000256|RuleBase:RU364048};
DE EC=1.13.11.- {ECO:0000256|RuleBase:RU364048};
GN ORFNames=LH20_08885 {ECO:0000313|EMBL:ALC12061.1};
OS Sphingopyxis sp. (strain 113P3).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingopyxis.
OX NCBI_TaxID=292913 {ECO:0000313|EMBL:ALC12061.1, ECO:0000313|Proteomes:UP000061305};
RN [1] {ECO:0000313|EMBL:ALC12061.1, ECO:0000313|Proteomes:UP000061305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=113P3 {ECO:0000313|EMBL:ALC12061.1,
RC ECO:0000313|Proteomes:UP000061305};
RX PubMed=26472829;
RA Ohtsubo Y., Nagata Y., Numata M., Tsuchikane K., Hosoyama A., Yamazoe A.,
RA Tsuda M., Fujita N., Kawai F.;
RT "Complete Genome Sequence of Polyvinyl Alcohol-Degrading Strain
RT Sphingopyxis sp. 113P3 (NBRC 111507).";
RL Genome Announc. 3:e01169-15(2015).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1,
CC ECO:0000256|RuleBase:RU364048};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1,
CC ECO:0000256|RuleBase:RU364048};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787, ECO:0000256|RuleBase:RU364048}.
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DR EMBL; CP009452; ALC12061.1; -; Genomic_DNA.
DR RefSeq; WP_053553860.1; NZ_CP009452.1.
DR AlphaFoldDB; A0A0M5ILC1; -.
DR STRING; 292913.LH20_08885; -.
DR KEGG; sphp:LH20_08885; -.
DR PATRIC; fig|292913.6.peg.1794; -.
DR OrthoDB; 6636843at2; -.
DR Proteomes; UP000061305; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF89; CAROTENOID 9,10(9',10')-CLEAVAGE DIOXYGENASE 1; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000256|RuleBase:RU364048};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU364048};
KW Reference proteome {ECO:0000313|Proteomes:UP000061305}.
FT BINDING 183
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 232
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 297
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 473
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 479 AA; 52781 MW; DC2DD04631F7913F CRC64;
MASNVETLIR SAVTKGIGKV AGFNRKRLPR PVDAHPYLTG IHRPMEEEMT LEELRVEGEI
PAALSGRYLR NGPNPALPPD PASYHWFTGA GMVHGIRIEG GAARWYRNRW VRGAEACAKL
GEEIPPGPRT EGSDAPNTNV VGLAGRTFAI VEAGGKPVEL SETLDTIAHN PFDATLAGPY
TAHPHHDPFT NETHAITYQG DQLNTVWHVV LDAEAHVIRE EAIAVADGPS IHDCAITENH
VLVFDLPVTF SMKSLLAGYR FPYAWNPAHP ARVGLLPRTG AGSEVIWVPV EPCYVFHPAN
AFETGDGKVI VDVAAHETMF AESKRGPDSP RSRMERWTID PVQGVTTRTV IHDHNQEFPR
YDERRTTRPY RYIYSVALPD GPGELEIADT RLFRHDLDRG VTDTRDFGPG RHPGEFVFVP
RAAEGAEDDG WLIGLVVDMN DETTDLVILN ADDFTGPPQA IVHLPHRVPP GFHGNWVAD
//
