ID A0A0M5J7L0_DROBS Unreviewed; 732 AA.
AC A0A0M5J7L0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=CG8907 {ECO:0000313|EMBL:ALC47694.1};
GN ORFNames=Dbus_chr3Rg2444 {ECO:0000313|EMBL:ALC47694.1};
OS Drosophila busckii (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=30019 {ECO:0000313|EMBL:ALC47694.1, ECO:0000313|Proteomes:UP000494163};
RN [1] {ECO:0000313|EMBL:ALC47694.1, ECO:0000313|Proteomes:UP000494163}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole larvae {ECO:0000313|EMBL:ALC47694.1};
RA Zhou Q., Bachtrog D.;
RT "Ancestral chromatin configuration constrains chromatin evolution on
RT differentiating sex chromosomes in Drosophila.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the EPS8 family.
CC {ECO:0000256|ARBA:ARBA00006197}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP012526; ALC47694.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M5J7L0; -.
DR STRING; 30019.A0A0M5J7L0; -.
DR OMA; RNTMALY; -.
DR Proteomes; UP000494163; Chromosome 3r sequence.
DR CDD; cd01210; PTB_EPS8; 1.
DR CDD; cd11764; SH3_Eps8; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR039801; EPS8-like.
DR InterPro; IPR033928; EPS8_PTB.
DR InterPro; IPR035462; Eps8_SH3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR013625; PTB.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041418; SAM_3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12287:SF23; AROUSER, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR12287; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN; 1.
DR Pfam; PF08416; PTB; 1.
DR Pfam; PF18016; SAM_3; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000494163};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 436..495
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 554..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..569
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 83557 MW; 529A139992EBC404 CRC64;
MVKPSNRTLK YFRPIVVQRS MLRNGYENGS QPSDRHNGAY EREEIKPTYS LEHLATFKLK
NEAEMKQPKE KMKLLIELDK TGGIWPHKMY MSFNGQWLVM LDSEMKEIEN FPGSLISEPT
AFISEDPQET YHNILIFSVP GISLGNTEMH IFQVSDVNAV HLVEDLRQLS SGSPVTVDRN
KTPILLPKPD RPGNHQAKDQ FGIAAAVAGI AAEKNAQDRE QTERDVQVLN HCFEDVERFI
ARLHYAAEAM HELESRKNEH NPHGEGLLVL RSRPPIESEF YDILAKIKLG LNYAVKLQNH
FTKGVDPVNN VFISLQTIVT VCNDVYNGMH LPESVVNPLL RRETVTFLNG TLDSGKKELW
YSLGNNWTVP KDQFKDHKGS YHPIFYDDWS PDWVVDEEVA YLAPAIKKPQ TPVPSPMMVP
PSPQLNRTWL SRLESRNVQI AEVVYNKSAT NDKELNVAKG EYLEIIDDSR NWWKARNSVG
NIGYVPHTVL QPYNFEHRPR DTDSLSSMPM EIVDANEPPI YRNTMALYSP PTDRESMQSV
GTAKNMPRSY SMPNVPVPPP MPPPSESQTP TPTGTMKRNM AAAGAMAAMR ARNDCDADDD
AYMLQEGVNE ELKMMLMQRQ RRRDLEILKT PEIYINQNSK PKEVEEWLRG KGFSDVIIKR
LHTLSGEEIF ALSSHTIESY FGQRESRRLI SQIVLQKNFC EYKTIRSSEL SAKLARARQK
ADQSNNDTDE IF
//
