ID A0A0M5L070_9GAMM Unreviewed; 400 AA.
AC A0A0M5L070;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Hydroxyglutarate oxidase {ECO:0000313|EMBL:ALE01573.1};
GN ORFNames=W908_02515 {ECO:0000313|EMBL:ALE01573.1};
OS Candidatus Pseudothioglobus singularis PS1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Candidatus Pseudothioglobus.
OX NCBI_TaxID=1125411 {ECO:0000313|EMBL:ALE01573.1, ECO:0000313|Proteomes:UP000068905};
RN [1] {ECO:0000313|EMBL:ALE01573.1, ECO:0000313|Proteomes:UP000068905}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PS1 {ECO:0000313|EMBL:ALE01573.1,
RC ECO:0000313|Proteomes:UP000068905};
RX PubMed=26494659;
RA Marshall K.T., Morris R.M.;
RT "Genome Sequence of 'Candidatus Thioglobus singularis' Strain PS1, a
RT Mixotroph from the SUP05 Clade of Marine Gammaproteobacteria.";
RL Genome Announc. 3:e01155-e01115(2015).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the L2HGDH family.
CC {ECO:0000256|ARBA:ARBA00037941}.
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DR EMBL; CP006911; ALE01573.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M5L070; -.
DR STRING; 1125411.W908_02515; -.
DR KEGG; tsn:W908_02515; -.
DR PATRIC; fig|1125411.7.peg.494; -.
DR Proteomes; UP000068905; Chromosome.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:UniProt.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR43104; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43104:SF2; L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000068905}.
FT DOMAIN 3..390
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
SQ SEQUENCE 400 AA; 44928 MW; 90FB23AB5FF235AD CRC64;
MYDYVVLGGG IVGVSTALSL INKHPDNKIL LIEKENSFAK HQTGHNSGVI HAGVYYQPGS
LKAEFCREGL KETISFCSDN NIPYEQCGKL LVATNKIELQ RMYELHERCK ANEIDVEALD
QKQLNEVEPN IIGIGALLVK STGIVDYKLI TKKMSEEFES KGGEFLLNSE VVNLEEDEEK
IKIITSRESL NSKYLICCAG LMADRIAKLL NIKINFQIVP FRGEYFRLPS KHNNLVKHLI
YPIPDPDLPF LGVHLTKMID GSITVGPNAV LGFKREGYSK FNFSIKDTLQ FLSFKGFHNV
IKKNLKSGLY EMKNSIFKRG YLKEVQKYSP QIKLNDLEHY PAGIRAQAVL EDGSLVHDFL
FAESRRSIHV CNAPSPAATS AIPIGKYITH KATEAFKKLS
//
