ID   A0A0M6XK08_9RHOB        Unreviewed;       833 AA.
AC   A0A0M6XK08;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:CTQ31439.1};
DE            EC=2.1.2.10 {ECO:0000313|EMBL:CTQ31439.1};
GN   Name=gcvT_1 {ECO:0000313|EMBL:CTQ31439.1};
GN   ORFNames=JAN5088_00197 {ECO:0000313|EMBL:CTQ31439.1};
OS   Jannaschia rubra.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Jannaschia.
OX   NCBI_TaxID=282197 {ECO:0000313|EMBL:CTQ31439.1, ECO:0000313|Proteomes:UP000048908};
RN   [1] {ECO:0000313|EMBL:CTQ31439.1, ECO:0000313|Proteomes:UP000048908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CECT 5088 {ECO:0000313|EMBL:CTQ31439.1,
RC   ECO:0000313|Proteomes:UP000048908};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
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DR   EMBL; CXPG01000009; CTQ31439.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M6XK08; -.
DR   STRING; 282197.SAMN04488517_101220; -.
DR   Proteomes; UP000048908; Unassembled WGS sequence.
DR   GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000313|EMBL:CTQ31439.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000048908};
KW   Transferase {ECO:0000313|EMBL:CTQ31439.1}.
FT   DOMAIN          9..381
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          385..437
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          440..722
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          744..823
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   833 AA;  92620 MW;  09BEAA7BE308BB4E CRC64;
     MRMKTHVRAL VVGGGAVGTS IAYHLAKAGW DTMLLERDEL TSGSTWHAAG LLPYFNMGYA
     TSHIHDYSIR FYKTLEEETG LNPGFSVVGN LRMAQTQARM DEYELYASLA ETVGIPHEWL
     TPADIADRYP LVRTDDLVGA ILHPTDGYIN PADVTMAMAR GARQHGATIE RRWQVDGYHW
     TGEHWDVTAT RMVERGGNLV ASDEQVTIHA EHVVTATGNH AQRTAQLLGI KTPAIVVEHQ
     YIVTEPDPAL VEWRKSNPQH PVLRDADAKW YVREERGGWI LGPYEQNAPA RFPFGVPDSF
     RADLFPLDLE RIEQEYMSFI HRIPSSENAG LKDDFNGPIC YTPDGNPLVG PAPGLRNMWL
     AEGFSFGITA AGGTGHYLAQ MMTSGEAEID MASLDPRRFG KWMTTEYAMR KNEEAYDHVY
     VLHHPDEERP ACRPLKTAPC YDRMKARGAQ FGCVNGWERP NYFGPLDAPD SFDHDSRSFR
     RGAWWGHAVT EAKAIREGVG MIDATAFTKH MLRGPGAAAF LDWFTTNKLP KVGRINLTYA
     LTEAGTTRTE YTIVRLAEDT FYLVSAGAWQ AYDSDFLAKA VNDKVNDFGP MWLDDCTGAH
     GVFALAGPRA RDVLRDLIVA PDPTFALSNK GFPWLSARRI ELGMVPVNAI RVAYTGELGW
     ELHHPMEMQN HLFDRLMAAG EAHGLTLVGA RAQNWLRQEK SYRAFGTELG RDATPLEAGL
     DRFVDLSKDF HGKAAMEETG IRSKCVTLLI DGPDDADPWG REALYAGDDR VGRLTSGGYS
     VAFGRSIGMG YVRPDLAVPG TPLQVRMQRA LWEAEVTEDS PYDPTNARIR ADG
//