ID A0A0M8JRU3_9CHLR Unreviewed; 500 AA.
AC A0A0M8JRU3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:GAP19165.1};
GN ORFNames=ADN01_00895 {ECO:0000313|EMBL:KPL91521.1}, LSAC_03065
GN {ECO:0000313|EMBL:GAP19165.1};
OS Levilinea saccharolytica.
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Levilinea.
OX NCBI_TaxID=229921 {ECO:0000313|EMBL:GAP19165.1};
RN [1] {ECO:0000313|EMBL:GAP19165.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=KIBI-1 {ECO:0000313|EMBL:GAP19165.1};
RA Matsuura N., Tourlousse M.D., Ohashi A., Hugenholtz P., Sekiguchi Y.;
RT "Draft Genome Sequences of Anaerolinea thermolimosa IMO-1, Bellilinea
RT caldifistulae GOMI-1, Leptolinea tardivitalis YMTK-2, Levilinea
RT saccharolytica KIBI-1, Longilinea arvoryzae KOME-1, Previously Described as
RT Members of the Class Anaerolineae (Chloroflexi).";
RL Genome Announc. 3:e00975-15(2015).
RN [2] {ECO:0000313|EMBL:KPL91521.1, ECO:0000313|Proteomes:UP000050501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIBI-1 {ECO:0000313|EMBL:KPL91521.1,
RC ECO:0000313|Proteomes:UP000050501};
RA Hemp J., Ward L.M., Pace L.A., Fischer W.W.;
RT "Genome sequence of Levilinea saccharolytica DSM 16555.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF967975; GAP19165.1; -; Genomic_DNA.
DR EMBL; LGCM01000003; KPL91521.1; -; Genomic_DNA.
DR RefSeq; WP_062419467.1; NZ_LGCM01000003.1.
DR AlphaFoldDB; A0A0M8JRU3; -.
DR STRING; 229921.ADN01_00895; -.
DR Proteomes; UP000050501; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050501};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 32..469
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 253..372
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 472..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 115..149
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 233..260
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 500 AA; 53421 MW; D9329E4E55FBC219 CRC64;
MKRSKPAASN QRLWQKKGIW AAVILFLAAC GGAAWYFLYG PQAVLAQSAS KAAAAVNTTL
VKKGDLSVTV SGSGVLEANR TVDLSFSTGG TVSDVHVQLG DMVKEGQVLA RLDNASSLEA
NVVSLQLKLL QAQKDLTDLQ QNADVSLAEA YQDWVTAKAA YQEAVAAQQR TAYARCSEEV
NTRYKTQLDQ ASSRMNELAV HSLGTDAWVD AKNTYDTALA NYTYCTTYTE SEKIEAQAAV
DVSKTKMDQA ERKYNTLKSA AGIDPSQLAL DEAAVETYRL QLIQAKEDLQ GMTLTAPMDG
KVVYLASGVG TIVDTSKFIS IADVSRPQLI VSVDESDIDH FVLSSPASVI FDALPDQTFH
GVITQVDPSL TSSGQYRILK GVLTLNTDAV RTVQNLPLGL NASVTIVYKE IKDALIIPVT
ALKKLNGEGY EVQLVDNDGT TRSQEVQIGL QDGTYAEVLS GLNEGDKIIA ITGNSSSSPS
SNPFTDGGMM MPGGGMPPPP
//
