ID A0A0M8KSM3_NICAT Unreviewed; 506 AA.
AC A0A0M8KSM3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=3-phosphoshikimate 1-carboxyvinyltransferase {ECO:0000256|ARBA:ARBA00012450, ECO:0000256|RuleBase:RU004164};
DE EC=2.5.1.19 {ECO:0000256|ARBA:ARBA00012450, ECO:0000256|RuleBase:RU004164};
GN Name=EPSPS-1_0 {ECO:0000313|EMBL:OIT07848.1};
GN ORFNames=A4A49_05371 {ECO:0000313|EMBL:OIT07848.1};
OS Nicotiana attenuata (Coyote tobacco).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC Nicotiana.
OX NCBI_TaxID=49451 {ECO:0000313|EMBL:JAI68043.1};
RN [1] {ECO:0000313|EMBL:JAI68043.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26306554; DOI=10.1111/tpj.12997;
RA Ling Z., Zhou W., Baldwin I.T., Xu S.;
RT "Insect herbivory elicits genome-wide alternative splicing responses in
RT Nicotiana attenuata.";
RL Plant J. 84:228-243(2015).
RN [2] {ECO:0000313|EMBL:OIT07848.1, ECO:0000313|Proteomes:UP000187609}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. UT {ECO:0000313|Proteomes:UP000187609}, and UT
RC {ECO:0000313|EMBL:OIT07848.1};
RC TISSUE=Leaves {ECO:0000313|EMBL:OIT07848.1};
RA Xu S., Brockmoeller T., Gaquerel E., Navarro A., Kuhl H., Gase K., Ling Z.,
RA Zhou W., Kreitzer C., Stanke M., Tang H., Lyons E., Pandey P., Pandey S.P.,
RA Timmermann B., Baldwin I.T.;
RT "The genome of Nicotiana attenuata.";
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-
CC carboxyvinyl)-3-phosphoshikimate + phosphate; Xref=Rhea:RHEA:21256,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:57701, ChEBI:CHEBI:58702,
CC ChEBI:CHEBI:145989; EC=2.5.1.19;
CC Evidence={ECO:0000256|ARBA:ARBA00001901,
CC ECO:0000256|RuleBase:RU004164};
CC -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis;
CC chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step
CC 6/7. {ECO:0000256|ARBA:ARBA00004811, ECO:0000256|RuleBase:RU004164}.
CC -!- SIMILARITY: Belongs to the EPSP synthase family.
CC {ECO:0000256|ARBA:ARBA00009948, ECO:0000256|RuleBase:RU004164}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GCZL01000003; JAI68043.1; -; Transcribed_RNA.
DR EMBL; MJEQ01037183; OIT07848.1; -; Genomic_DNA.
DR RefSeq; XP_019244994.1; XM_019389449.1.
DR AlphaFoldDB; A0A0M8KSM3; -.
DR STRING; 49451.A0A0M8KSM3; -.
DR EnsemblPlants; OIT07848; OIT07848; A4A49_05371.
DR GeneID; 109224880; -.
DR Gramene; OIT07848; OIT07848; A4A49_05371.
DR KEGG; nau:109224880; -.
DR OMA; ARIGFTR; -.
DR OrthoDB; 865at2759; -.
DR UniPathway; UPA00053; UER00089.
DR Proteomes; UP000187609; Chromosome 1.
DR GO; GO:0003866; F:3-phosphoshikimate 1-carboxyvinyltransferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd01556; EPSP_synthase; 1.
DR Gene3D; 3.65.10.10; Enolpyruvate transferase domain; 2.
DR HAMAP; MF_00210; EPSP_synth; 1.
DR InterPro; IPR001986; Enolpyruvate_Tfrase_dom.
DR InterPro; IPR036968; Enolpyruvate_Tfrase_sf.
DR InterPro; IPR006264; EPSP_synthase.
DR InterPro; IPR023193; EPSP_synthase_CS.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR NCBIfam; TIGR01356; aroA; 1.
DR PANTHER; PTHR21090:SF31; 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE; 1.
DR PANTHER; PTHR21090; AROM/DEHYDROQUINATE SYNTHASE; 1.
DR Pfam; PF00275; EPSP_synthase; 1.
DR SUPFAM; SSF55205; EPT/RTPC-like; 1.
DR PROSITE; PS00104; EPSP_SYNTHASE_1; 1.
DR PROSITE; PS00885; EPSP_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605,
KW ECO:0000256|RuleBase:RU004164};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141,
KW ECO:0000256|RuleBase:RU004164};
KW Reference proteome {ECO:0000313|Proteomes:UP000187609};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004164}.
FT DOMAIN 70..500
FT /note="Enolpyruvate transferase"
FT /evidence="ECO:0000259|Pfam:PF00275"
SQ SEQUENCE 506 AA; 54262 MW; 85C594DB8B4DBF64 CRC64;
MAQISNMAQG IQTLYPNSNI HKPQILTFSP SLSFGLKNSA KSMWVLKKDS IFRISASVAT
TQKPTEIVLQ PIKEISGTVK LPGSKSLSNR ILLLAALSEG TTVVDNLLSS DDIHYMLGAL
KTLGLNVEED SANQRATVEG SGGLFPVGKE SNEEIQLFLG NAGTAMRPLT AAVAVAGGNS
RYVLDGVPRM RERPIGDLVD GLKQLGAEVD CFLGTKCPPV RIVSKGGLPG GKVKLSGSIS
SQYLTALLMA APLALGDVEI ETIDKLISIP YVEMTLKLME RFGISVEHSS SWDRFAVRGG
QKYKSPGKAY VEGDASSASY FLAGAAVTGG TVTVEGCGTS SLQGDVKFAE VLEKMGAEVT
WTENSVTVKG PQRNSSGMKH LRAIDVNMNK MPDVAMTLAV VALFADGPTA IRDVASWRVK
ETERMIAICT ELRKLGATVE EGPDYCIITP PEKLNVTEID TYDDHRMAMA FSLAACADVP
VTINDPGCTR KTFPNYFDVL QQYSKH
//
