ID   A0A0M8MVS4_9HYPO        Unreviewed;      1511 AA.
AC   A0A0M8MVS4;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   22-FEB-2023, entry version 17.
DE   RecName: Full=THO complex subunit 2 {ECO:0000256|ARBA:ARBA00019596};
GN   ORFNames=ESCO_005376 {ECO:0000313|EMBL:KOS20366.1};
OS   Escovopsis weberi.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Escovopsis.
OX   NCBI_TaxID=150374 {ECO:0000313|EMBL:KOS20366.1, ECO:0000313|Proteomes:UP000053831};
RN   [1] {ECO:0000313|EMBL:KOS20366.1, ECO:0000313|Proteomes:UP000053831}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   de Man T.J., Stajich J.E., Kubicek C.P., Chenthamara K., Atanasova L.,
RA   Druzhinina I.S., Birnbaum S., Barribeau S.M., Teiling C., Suen G.,
RA   Currie C., Gerardo N.M.;
RT   "The genome of the fungus Escovopsis weberi, a specialized disease agent of
RT   ant agriculture.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the THOC2 family.
CC       {ECO:0000256|ARBA:ARBA00007857}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS20366.1}.
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DR   EMBL; LGSR01000017; KOS20366.1; -; Genomic_DNA.
DR   STRING; 150374.A0A0M8MVS4; -.
DR   OrthoDB; 179356at2759; -.
DR   Proteomes; UP000053831; Unassembled WGS sequence.
DR   GO; GO:0000347; C:THO complex; IEA:InterPro.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   InterPro; IPR040007; Tho2.
DR   InterPro; IPR021418; THO_THOC2_C.
DR   InterPro; IPR021726; THO_THOC2_N.
DR   InterPro; IPR032302; THOC2_N.
DR   PANTHER; PTHR21597:SF0; THO COMPLEX SUBUNIT 2; 1.
DR   PANTHER; PTHR21597; THO2 PROTEIN; 1.
DR   Pfam; PF11262; Tho2; 1.
DR   Pfam; PF11732; Thoc2; 1.
DR   Pfam; PF16134; THOC2_N; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053831}.
FT   DOMAIN          16..746
FT                   /note="THO complex subunit 2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16134"
FT   DOMAIN          748..823
FT                   /note="THO complex subunitTHOC2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11732"
FT   DOMAIN          1110..1445
FT                   /note="THO complex subunitTHOC2 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11262"
FT   REGION          406..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1050..1088
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1146..1168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1469..1511
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..432
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..477
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1068..1088
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1491..1511
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1511 AA;  170563 MW;  7110CD156066BC81 CRC64;
     MGPSSPAVSN YRYDNLTDEK LRSWAERGRE DIVRHGVQSR DDVDITELSS LFQEFIYAVV
     ENRLNPTDAG ACVRDILGVE TSDVIKDSYA FAPHTLLLDS LAIVMDNDAD LYRPSLREFL
     IATGVSPALM RQVLDAPLLQ QLGLIRDTFA RLGVRQATNL LYRQANYNLL REETEGYSKL
     VTELFTTSSV VTPSPELAEQ TFERVKALIG TFDLDVGRVL DVTLDVAAAV LIKQYKFFVK
     FLRISSWWPR PPQSAPNSSS YTGGLPIWAE PNYPLWNTTD EDEILIAERR LLRDAAFWER
     AREAQLAAFF ELGGRTIANS NGQLKIANGA GAESGSDISR QWIEETKTLP PPGNKVAAQL
     LGFKLLFYNS DLRDKTDVLP ANLLYLAALL IKVGFLSLTD LYPHLSPPDE EMERVREEQI
     SLNEKEERDT KGGPMNALLM AGVLPQGEDD NPISLGLPRR EPPKKVEPEA KPAVAENVED
     PKALPKPLEQ KVGLLVQLLT IGAVPESLFI LGRFPWIPDV FPDVLPRIHR ILHVMVDKVF
     KESRPRPFDA MDCPTKDMYA VDQTGMAKGS VRLTKIQVKR AWRWPYPDKW DTNENQNYRF
     YWDEWADNIP VCQTVDDIFT LCNTFLNISG VNVGKDESLL SKLASIGAKS LADDASESNH
     ARWLDLLRRL LVPALSHTKA NASVVNAIWE LLKRYPLSTR YSIYAEWFEG QISRLPAMRT
     AFAKATSETR GTMKRVSLTN LSEMAKQLAK TSYSSPGIVF RVAFEQLESY PNLIEAFVEC
     AKYFTDLSYD VLVWSLMSSL GKSRSRTQAD HALTTSKWLQ ALSRFSGKVF KRYPGLNPTP
     VLQYVNDQLA RGNSTDLIIL KEFITSMGGI VDAMDFTDYQ ILSMAGGERL RRHTLIRAQD
     KRFDNTKSSK RLIRALTDSR LAARFLLNLA QYRQSAIFQI PEDEAHIKYL SSLVDDSHQT
     LIQYLDFLWS NLDPASFDAL LPSIPDLLRS FGLDTSLAFL IGRASLSHRL YPWGGKEMDG
     NKDENQSVLQ EAADKEGDIS MSDIKALDEA AAAKDKPTAE DQVGEEQPKI PQPTTNATPF
     LQKSDDPSLT LAPLQPLVEA VKTTVPSEIW QKMTPELYAV FWALNLGDLF CPEEMYKNEK
     DRLEGEGQAI MKDRSDMTRR GQERKNEKRQ ELLKLQLSLS MELKEHRQRK TKWRDCLTEQ
     FQTSFPNVKA KTDSISDVLL EQCFLPRVFL SPADTEYTYK FIMALHECRA PKFKLMSLYD
     RFFNANRLRA LIFTSSVREA EYLGRFLRLI LKDLSRWHKN EPITGDKPLR ASKDQSRLGA
     FDKEARGPSD RPFRGFALTV DEKGEPETLM EHAQFQDLLF RWHKNLNTAL KSCLAGTEWM
     HIRNAITVLR AVLDFFPAVD FMATQFLNQL QKITKQEAAS KTAPDNEEGH RVDLSVAAQG
     AMSELQKRKP KWVLVQAFRP NAVSSLLQTI STDSTPTNIA KAGGPQAEAD KAATPNSSRP
     TATETKPQSS K
//