ID A0A0M8MYU2_9BASI Unreviewed; 728 AA.
AC A0A0M8MYU2;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Tbc-domain-containing protein {ECO:0000313|EMBL:KOS16291.1};
GN ORFNames=Malapachy_2958 {ECO:0000313|EMBL:KOS16291.1};
OS Malassezia pachydermatis.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia.
OX NCBI_TaxID=77020 {ECO:0000313|EMBL:KOS16291.1, ECO:0000313|Proteomes:UP000037751};
RN [1] {ECO:0000313|EMBL:KOS16291.1, ECO:0000313|Proteomes:UP000037751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 1879 {ECO:0000313|EMBL:KOS16291.1,
RC ECO:0000313|Proteomes:UP000037751};
RA Triana S., Ohm R., Gonzalez A., DeCock H., Restrepo S., Celis A.;
RT "Draft Genome Sequence of Malassezia furfur CBS1878 and Malassezia
RT pachydermatis CBS1879.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS16291.1}.
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DR EMBL; LGAV01000001; KOS16291.1; -; Genomic_DNA.
DR RefSeq; XP_017993923.1; XM_018137441.1.
DR AlphaFoldDB; A0A0M8MYU2; -.
DR STRING; 77020.A0A0M8MYU2; -.
DR GeneID; 28729317; -.
DR VEuPathDB; FungiDB:Malapachy_2958; -.
DR OrthoDB; 3034081at2759; -.
DR Proteomes; UP000037751; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000195; Rab-GAP-TBC_dom.
DR InterPro; IPR035969; Rab-GAP_TBC_sf.
DR PANTHER; PTHR47219:SF20; GTPASE ACTIVATING PROTEIN GYP2; 1.
DR PANTHER; PTHR47219; RAB GTPASE-ACTIVATING PROTEIN 1-LIKE; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF00566; RabGAP-TBC; 1.
DR SMART; SM00164; TBC; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50086; TBC_RABGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000037751}.
FT DOMAIN 246..434
FT /note="Rab-GAP TBC"
FT /evidence="ECO:0000259|PROSITE:PS50086"
FT DOMAIN 627..662
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 728 AA; 83077 MW; 8F18760599A9DC2C CRC64;
MSTIVHSLRD YRTPTKAQQF AQAFGLPDDE APYVDAAGNR AEILSAILSL STPDMDGAQE
DLVFAGRLTL TPSFLCFASQ GDRGRGCRIA IPLSTVRRVE RLNTRDVVFA LGITVWHGTH
MIFQLNALRP SCEGFCNAMR VRLRAHLGEM KQLQPFLDSC YSEFLLKQSQ DDVQEKGKGK
EGTEADASEA LKPYQMGLGA TFGFPGDPKK LKEKSKMRLW KEYLRLHGRN ITLLRYPQFT
KLVQVGLPNM LRGEIWEVSS GSIFQRMAHP GLYESLLRDH EGKTNLSTEE IEKDLNRSLP
EYAAYQSPEG IETLRRVLVA YSWKNRELGY CQAMNIVVAA LLIYMSEEQC FWVLDTLCDR
LLPGYYTQSM AGTLLDQKVF ENLVQQTMPV LHEHFVKNDM QLSIVTLPWL LSLYINSMPM
VFAFRIIDCF MAFGAQVLFQ VGLAILKING EAILSVTDDG TMIGLLRNYF RSLGDSAYPE
SMDERRRQIT KFQQLLVIAF REFSVVTNDT IDHERKRFRQ QIVQEIEAFA RRSAIRNLHF
HGRFTKPQLI LIYDHVVESI YRARHAPESL TQGEHKVLSA ADPTQDLKEM RVNFTTFRLF
LSEIATWARD EYIVSNGFQE RIERRVPDQT LARRIFDYWD KDKCGSLTLQ DIVTGLDEIM
FLDGDMAGAT AWFFRLHANG KEKLSKNDIL ALSESLLFMF RNEPGDEHLG SISTLISRAF
EMAGTSDA
//
