ID   A0A0M8MZE8_9HYPO        Unreviewed;       590 AA.
AC   A0A0M8MZE8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=KsdD-like steroid dehydrogenase {ECO:0000313|EMBL:KOS21918.1};
GN   ORFNames=ESCO_002077 {ECO:0000313|EMBL:KOS21918.1};
OS   Escovopsis weberi.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Escovopsis.
OX   NCBI_TaxID=150374 {ECO:0000313|EMBL:KOS21918.1, ECO:0000313|Proteomes:UP000053831};
RN   [1] {ECO:0000313|EMBL:KOS21918.1, ECO:0000313|Proteomes:UP000053831}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   de Man T.J., Stajich J.E., Kubicek C.P., Chenthamara K., Atanasova L.,
RA   Druzhinina I.S., Birnbaum S., Barribeau S.M., Teiling C., Suen G.,
RA   Currie C., Gerardo N.M.;
RT   "The genome of the fungus Escovopsis weberi, a specialized disease agent of
RT   ant agriculture.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS21918.1}.
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DR   EMBL; LGSR01000006; KOS21918.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8MZE8; -.
DR   STRING; 150374.A0A0M8MZE8; -.
DR   OrthoDB; 1819728at2759; -.
DR   Proteomes; UP000053831; Unassembled WGS sequence.
DR   GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR014614; KsdD_DH.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR   PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR   PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   PIRSF; PIRSF036654; UCP036654; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053831}.
FT   DOMAIN          16..550
FT                   /note="FAD-dependent oxidoreductase 2 FAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF00890"
SQ   SEQUENCE   590 AA;  64619 MW;  9FF726D83B8567E9 CRC64;
     MASEGESSTP NLTTPVIIIG HGLAGLVAAY ELSLRNVPTV ILDQENENNV GGQAHWSLGG
     LFFVDSPNQR RLGIKDSRGL AMRDWLGSAQ FDREDEDYWP RKWAEAFVNF ATDEFAEYVS
     SKGLKVANVG WAERGDGTAD GHGNSVPRFH LTWGTGPEVV RIFREPVEEA AKRGVVEFKF
     RHMVDEIKVD PVSGRAIGVK GRILQPVDSE RGVKSSREPF GDFELLGSAV LIASGGIGGD
     LDKVKASWPV DRLGSKVPEN FVIGVPNHVD GRMIDISQSA GARVINRDRM WHYTEGLQNW
     DSIWPGHGIR ILPAPSSIWL DATGKRFPPN VYPGSDTLGT LRHICATGYD YSWFILDQTI
     IAREFALSGS EQNPDVTGKS FWKTLINRLF NSKGTENVQK FVQNGRDFVV ADDLEDLVAG
     MNKLAEERLG PALDPHKIRK VVEARDDQVV NSYSKDAQIM LMRNARAYWP DRWSRVATPH
     RILDKAYGPL IAVRLNLLSR KTLGGIETNL KSNVMRRDKT PFPGLYAAGE AAGFGGGGVH
     GYNALEGTFL GGCIFSGRAA GRAMADEALG HQLGPAILTG RKNSTASNSV
//