ID   A0A0M8P0Q7_9EURO        Unreviewed;       351 AA.
AC   A0A0M8P0Q7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN   ORFNames=ACN38_g5963 {ECO:0000313|EMBL:KOS43126.1};
OS   Penicillium nordicum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS43126.1, ECO:0000313|Proteomes:UP000037696};
RN   [1] {ECO:0000313|EMBL:KOS43126.1, ECO:0000313|Proteomes:UP000037696}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS43126.1,
RC   ECO:0000313|Proteomes:UP000037696};
RA   Nguyen H.D., Seifert K.A.;
RT   "Genome sequencing of Penicillium nordicum.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + H2O + N(6)-methyl-AMP = IMP + methylamine;
CC         Xref=Rhea:RHEA:16001, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:58053, ChEBI:CHEBI:59338, ChEBI:CHEBI:144842;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16002;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS43126.1}.
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DR   EMBL; LHQQ01000088; KOS43126.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8P0Q7; -.
DR   STRING; 229535.A0A0M8P0Q7; -.
DR   OrthoDB; 20281at2759; -.
DR   Proteomes; UP000037696; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF42; ADENOSINE DEAMINASE-LIKE PROTEIN; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037696}.
FT   DOMAIN          16..337
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   351 AA;  39265 MW;  0D7329B6454EC4C6 CRC64;
     MDDSKPVDRR FTKALPKIEL HAHLSGSISR QCLHEIWKRK KKQNPNLDVE DPLVLMPPGK
     VDYTLETFFS TFSKLTYQLC NDQDSLVYAT NSVLEDFLGD GVVYLELRTI PRASPDITQE
     QYINSVLDTT EKFRSKTKRM SVFLILAIDR GSMTAAEADE IVNLAIENKS RGVVGVDICG
     NPTKGDVSIY KEPFAKAKAN GLGITLHFAE TISSASASEL STLLSFQPDR LGHVIHVPDE
     IKKEIARRKL SLELCISCNV HAKMINGGFL DHHFGYWRHE DCPIALCTDD VGFFCSPVSN
     EYLLAAQHFG LSRTDLLEMC IKSAEGIFAG EYYKGRIQGM LEVFATRFDS A
//