ID A0A0M8P1P0_9EURO Unreviewed; 804 AA.
AC A0A0M8P1P0;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Elongator complex protein 2 {ECO:0000256|ARBA:ARBA00020267};
GN ORFNames=ACN38_g7406 {ECO:0000313|EMBL:KOS41707.1};
OS Penicillium nordicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS41707.1, ECO:0000313|Proteomes:UP000037696};
RN [1] {ECO:0000313|EMBL:KOS41707.1, ECO:0000313|Proteomes:UP000037696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS41707.1,
RC ECO:0000313|Proteomes:UP000037696};
RA Nguyen H.D., Seifert K.A.;
RT "Genome sequencing of Penicillium nordicum.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA
CC biosynthesis. {ECO:0000256|ARBA:ARBA00005043}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the WD repeat ELP2 family.
CC {ECO:0000256|ARBA:ARBA00005881}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS41707.1}.
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DR EMBL; LHQQ01000124; KOS41707.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8P1P0; -.
DR STRING; 229535.A0A0M8P1P0; -.
DR OrthoDB; 22040at2759; -.
DR UniPathway; UPA00988; -.
DR Proteomes; UP000037696; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0033588; C:elongator holoenzyme complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR037289; Elp2.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44111; ELONGATOR COMPLEX PROTEIN 2; 1.
DR PANTHER; PTHR44111:SF1; ELONGATOR COMPLEX PROTEIN 2; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 11.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000037696};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 54..90
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 105..146
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 207..253
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 292..326
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 398..428
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 659..693
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 804 AA; 88174 MW; 5AC14A3FEA4C4975 CRC64;
MVAIETDYIS VGGNRHPGAA DWDVQTGVLA FGADNNVALW DPLDKTERGI YSLLVGHTDK
VSVVRFYTCP ASGTRFIVTG SVDRTIRVWQ QNNANPHKYV LASTLEGHTG SVNAIAVADG
TDIITSGAAD GTVRIWRINA QHELKCELLE TITMTPRFFP LSLSLQGLEG DSDMPLVLAV
AGTTTKVQIY VSETSISQPE FKRRAVLAGH EAWIKALSFT HDKQSNGDIL LASASQDRYI
RLWRLRRGEA SAPAPIDDTD PLLGGMEPTL SNKAHEFEAA GSKYSITFEA LLFGHEDWIY
TIAWNPDSKR QQLLSASADN TITIWEQDQA SGVWMSAERM GEISVQKGST TATGSAGGFW
IGLWSPDGKQ VVSLGRTGSW RVWRHDSNSD LWIQRFGISG HVRSANGVQW EPTGGYLLST
SSDQTTRLHA KWVRKNTGSW HEFSRPQIHG YDLNCVDTLG PSQFVTGAEE KLLRVFNEPK
PIAQLLERLT GFKQSNDEDL PDTAEIPVLG LSNKALGDEA PVEEDEQKAP TEALIASASL
AANHPPLEDQ LSRYTLWPEH EKLYGHGYEI SAVAVSHDRR LIATACKASS IDHAVIRLYD
TSDWHEIKPS LTAHSLTITD LSFSSDDRYL LSVGRDRQWA VFQRSDADPT TFTNLSVNPK
GHSRMILGAA WAPATTDHVF ATAGRDKSVK IWQKSEDTFV CKTTVGLTSA VSAIGFLPAT
YKGTYVIAVG EDNGVISIHR ISADTLEAQH VVTIDKVASP SKTITQLSWR PVSAVEVDSR
DQFELAVASE DTSTRIYAIS NMLS
//
