ID A0A0M8P237_9EURO Unreviewed; 2234 AA.
AC A0A0M8P237;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=ACN38_g9429 {ECO:0000313|EMBL:KOS39724.1};
OS Penicillium nordicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS39724.1, ECO:0000313|Proteomes:UP000037696};
RN [1] {ECO:0000313|EMBL:KOS39724.1, ECO:0000313|Proteomes:UP000037696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS39724.1,
RC ECO:0000313|Proteomes:UP000037696};
RA Nguyen H.D., Seifert K.A.;
RT "Genome sequencing of Penicillium nordicum.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS39724.1}.
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DR EMBL; LHQQ01000190; KOS39724.1; -; Genomic_DNA.
DR STRING; 229535.A0A0M8P237; -.
DR OrthoDB; 2209130at2759; -.
DR Proteomes; UP000037696; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR CDD; cd05918; A_NRPS_SidN3_like; 2.
DR CDD; cd19545; FUM14_C_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF3; SIDEROPHORE SYNTHETASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000037696}.
FT DOMAIN 591..666
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1690..1766
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 885..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1588..1608
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2234 AA; 246448 MW; 7BD1867BA0E5FDE7 CRC64;
MMPESEVSQT GALIVTEQDL KQIWTWNAHR PKPHAASLHS IIAQWASELP GRLAVDAWDG
SFTFLELDCC SSQLAQHLSE FGVRESVVVP LAFERSRFTV VAMLAVLKLG AAFLLLDAGL
PESRLKNIVE QVKAEVVLAS PVYLQLAGRL AATVVTVPVT DRTSDSGSES CSSSSAVSMD
ARCPLDPLST TACIVFTSGT TGTPKGILIS HSNLVSTFNY TAKTVSLNET TRMLDSASYG
FDAAIYQALG TLSMGGCLCV PSDSERLTSI ASVIEKFQVN TAILTPSVAR LVDPRDVPSL
KRLKLVGEPP SPGLIDKWLP YSTLVMGYGP SECAVCSNAG VFYRDSTAEN NIGPALGCCA
WIVNPDDHNI LLPVGRVGEM LLEGPNVGQG YLNDKERTYA AFVNSPRWLT SGFSFMRGRN
GTLYKTGDLV QYERDGSILY IGRKDQQKKL HGQRIDLAEI EHAMVQTLPI KMEVIAEMCT
TAVSPSESQL IAFCCLTSPK PLVEQNPPSE IAGGTSILLP ASKKFLATSQ QIREKLQLHL
PSYMIPTFIF PVSEIPRAKP SDKLDRKRVV QEVGQLSQTQ LRKYFPASSK QLNTHKEKLL
QTMLREVLAL DIDILTDDHF FRLGGDSITA IQLIAIARKQ GMLLLMSDVL NHDNLADLAS
RMADIEDTGK VIEPIPAFSL LPSEQQELAL QKAKEQYDID AASIDDILPC TPLQEGMMAL
GQQRLGGNIA QRIFDLAPGT ELGRLKDAWK TVSQLNSILR TRIIDTSTKL LQVVIRDPLI
VEEYDDLKLD TESTMSFIIS RMGLGAPLVD VAILLSDEHK RPDRLTWTAH HAACDGWQVP
QIFAQVECAY RGDVALPEVD FSHFVKYITE ADNEKQDIYW KTQLAGPTPS TFPPSHQKSS
SERANESKNL PVYLGNLAKR GFLLATSINL AWSMVIAAYV ESPDVIFGLT LTGRNAPVAG
IESMTGPTIT TVPFRHLLDH SLKVDQALDR IQKQLSNMVP FEQAGLQNIR RTSPEAASAC
NLQSLLIIQP AMVNDVPHEV LINGEEVKSR LAFSNYPLTM ECTISPGEQL VNLSTQFNSH
IIHPDQMIHI LHQFGHVLRQ IHENSDVPLQ KINMLSPFDL ERLTDWNNAC PVAASHTLNQ
SVETHSAAEP KRQAVDAWDG SLTFQELDTF ASQFANHLQQ LGVHPEDVVP VCLEKSRLVP
VVMLAILKTG ASCTLVDDRL PQNRVNQMLS NSRARYFVCS ETSHNQFDLS QTDAKKLLVT
LDLIQQLPSC TNSVWNTNPD TPAFVVYTSG STGRPKGVVL EHRALSTSIL AHGAALKIGR
ESRMLQFASC SFDINLYEHM TTLVLGGCVC IPSNDARMNQ PAQYARESGA NITLSTPTVM
RALGQEDIST MQMISLGGEP ITHDVVEIWK QRAQVCNGYR PAECTICAIH PIEEQDGVNP
LATIGRGLGC IFWVVDIADS SRLAPVGVVG ELYIEGPILA RGYLNDSEST AKAFLSPPGW
LRRFRPNGSG DRVYKTGDLV RYNTDGTVVF VGRRDTQTKL RGQRIELSGV EYHLKNQLVN
SSIVVEVASL LGTNYLVGFV ENHNQSGITG DSSVQDSPSN DEQLSTGQTH APEFSFKAFS
ESREEDSRAL QALSLALPPY MVPSLILRVT TMPKTMTGKM DRKALREAVS KLTLDDVSLA
TQCSKNEHRL PSTDVEIKLR NLWAEILRLP KDSIGADDNF LARGGDSIAA MRLVSSGRSR
GIHLTVQDVL MAPKLSSMAE IAAEKLPSHN TPKQSNGQNV WEPFHALPNE ANTRQELIHD
ILRPLEMDVE KISDIIPATS LQEFALSNCA TFFVFNVGDR LDINKAILTG EALVAQHDVL
RTLFAFHKGR FYQVILKSLP KIPHVVHTIA EDTDAALDQL LRDTGASEPL PMGSSPLKFV
TVNTPQSRYL VLRMSHSQYD GFSISEFWGD WGLAFDDHPL PPRRSYADFV YSSDALGEHG
GYSYWKCLLS GSSMTYLATP PADTIGTDGN SQLVERKTVV ENFHSPPGIT LATFVQGVWV
MTLARWTRKR DIIFGLVTSG RRSKRHDFDT VMGPCLQIMP VRAKLQNDWS MHDLCQILQR
QGTDSMEFEG MELSRIKEHC TEWDPNAPLG TWVQHDNTDW NATLVLGGTD YGTPRVYDEP
YGQYDIGLES MSLGDGRLEV KLSSPSYLLN DEIFEGLRKM TVQMMEDLSA NLDVMLVTFL
PAETGLDNPT THFR
//
