ID   A0A0M8P2R1_9EURO        Unreviewed;       965 AA.
AC   A0A0M8P2R1;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   13-SEP-2023, entry version 24.
DE   RecName: Full=AMP deaminase {ECO:0000256|ARBA:ARBA00012775};
DE            EC=3.5.4.6 {ECO:0000256|ARBA:ARBA00012775};
GN   ORFNames=ACN38_g5127 {ECO:0000313|EMBL:KOS43958.1};
OS   Penicillium nordicum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX   NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS43958.1, ECO:0000313|Proteomes:UP000037696};
RN   [1] {ECO:0000313|EMBL:KOS43958.1, ECO:0000313|Proteomes:UP000037696}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS43958.1,
RC   ECO:0000313|Proteomes:UP000037696};
RA   Nguyen H.D., Seifert K.A.;
RT   "Genome sequencing of Penicillium nordicum.";
RL   Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- PATHWAY: Purine metabolism; IMP biosynthesis via salvage pathway; IMP
CC       from AMP: step 1/1. {ECO:0000256|ARBA:ARBA00004955}.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS43958.1}.
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DR   EMBL; LHQQ01000070; KOS43958.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8P2R1; -.
DR   STRING; 229535.A0A0M8P2R1; -.
DR   OrthoDB; 20951at2759; -.
DR   UniPathway; UPA00591; UER00663.
DR   Proteomes; UP000037696; Unassembled WGS sequence.
DR   GO; GO:0003876; F:AMP deaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0032264; P:IMP salvage; IEA:UniProtKB-UniPathway.
DR   CDD; cd01319; AMPD; 1.
DR   Gene3D; 4.10.800.20; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR006329; AMPD.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   NCBIfam; TIGR01429; AMP_deaminase; 1.
DR   PANTHER; PTHR11359; AMP DEAMINASE; 1.
DR   PANTHER; PTHR11359:SF0; AMP DEAMINASE; 1.
DR   Pfam; PF19326; AMP_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
DR   PROSITE; PS00485; A_DEAMINASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000037696}.
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          104..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          848..965
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..33
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        126..153
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        866..934
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   965 AA;  107798 MW;  F964E528E9CD0C76 CRC64;
     MGPPQSDLSS SRNANSAADS SNDESTTSPS GLKGPVDSPL HESTNALDQP AEDILPRDQQ
     QKTATYDYAY EKSMSHAEAR LFYQQHQLSA RNDTTLPLSP VATARSAVEH PEDSPVDLPD
     PMNTQGRVSR EGSMVLDSEP STLRLQSANE PDPSASHYLE DDEDGANGSA RNEAVLLGAA
     LGQGPYFAEN LQSAGVGIGG PQIASGFTSS NDAVTSELNA IYCKIKKLLD RRSQYMELSM
     QGPGNDPKDQ PDWEIYPPPP EPAWDDGKEY QPGNLGDPSD LGGKKRKMGQ DIGEDFDMEE
     LMPLPKESPW TYRLDGNSVY QVFDSEAAAD QQTPIVQIPS LRDFYMDLDA VVDVSTDGPA
     KSFAFKRLSY LEGKFQLYTL LNEYQEMADS KKVPHRDFYN VRKVDTHVHH SACMNQKHLL
     RFIKSKMRKS PDEVVLFRDG KHLTLREVFE SINLTAYDLS IDTLDMHAHT DSFHRFDKFN
     LKYNPVGESR LREIFLKTDN YIKGRYLAEI TKEVISDLES SKYQMVEWRI SIYGRSLQEW
     DKLAAWVVDN KLFSPNVRWL IQVPRLYDVY KASGMMENYE QVITNVFQPL FEVTKDPSSH
     PKLHIFLQRV VGFDSVDDES KPERRLYRKY PIPREWSTKQ NPPYTYWLYF MFANIASLNN
     WRKRRGFNTF VLRPHCGEAG DPDHLAVGFL CCHSISHGIL LRKVPLLQYL YYLDQIGIAM
     SPLSNNALFL TYDKNPCATF FRRGLNVSLS TDDPLQFAFT KEPLIEEYSV AAQIYKFSAV
     DMCELAKHSV DQSGFELSLK ERWLGSKCSV PGTAGNNVAK SNVPDIREAF RHETLLGELA
     LIERYSEGNG TGEQKSLAPG PPGEVVSSNH DQSAHNLESR PELGSSAANT VDASPSEAHG
     TNQMAISPTT PSKYLARSPR LGTGEFSSSS GSPALGAGVG GADGPPEQKI FPGIVHERAR
     KGNMQ
//