ID A0A0M8P5I9_9EURO Unreviewed; 392 AA.
AC A0A0M8P5I9;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0000259|Pfam:PF00891};
GN ORFNames=ACN38_g5160 {ECO:0000313|EMBL:KOS43967.1};
OS Penicillium nordicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS43967.1, ECO:0000313|Proteomes:UP000037696};
RN [1] {ECO:0000313|EMBL:KOS43967.1, ECO:0000313|Proteomes:UP000037696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS43967.1,
RC ECO:0000313|Proteomes:UP000037696};
RA Nguyen H.D., Seifert K.A.;
RT "Genome sequencing of Penicillium nordicum.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS43967.1}.
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DR EMBL; LHQQ01000070; KOS43967.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8P5I9; -.
DR OrthoDB; 2158293at2759; -.
DR Proteomes; UP000037696; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43712:SF18; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14240)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000037696};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..392
FT /note="O-methyltransferase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005819468"
FT DOMAIN 233..368
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 304
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 392 AA; 42422 MW; 2EACCD7B763B1C0F CRC64;
MSFLTRLASL LGLSSPAPAV APPGAALAAT VTVPASLGFV PVAIHFDLFN ILVGHGGPAT
ADEISAICNA RIKARGENEP ELSTRLASDT LYIMAGLSLV ERVAEDCFTA NAITNHMVAM
PSAQHGALHF TTEGLMAGAF LMKKLQDTRF AYPFADADGP LQYAYRLMGQ SELAEQHTYS
IMETQGRMDS FNHFMVGKFL KFGTFPDRVK SMGYELDSAL AGDTTTNTST SSATMVDIGG
GRGELLLEVQ AAYPHLGAED LIVQEFNADI DSVPGVRLMK WNYKEEAEQP VCGACVYALQ
HILHNLPDLD AVALLQKISR AMVPGSRVLI IEYAKNLTYT SLHASMIALY GGRERSSVEW
RQMAGLCGLE VTFEVYVKAG ESLVEMRRIV QS
//
