ID A0A0M8PC00_9EURO Unreviewed; 235 AA.
AC A0A0M8PC00;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=ACN38_g4011 {ECO:0000313|EMBL:KOS45011.1};
OS Penicillium nordicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS45011.1, ECO:0000313|Proteomes:UP000037696};
RN [1] {ECO:0000313|EMBL:KOS45011.1, ECO:0000313|Proteomes:UP000037696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS45011.1,
RC ECO:0000313|Proteomes:UP000037696};
RA Nguyen H.D., Seifert K.A.;
RT "Genome sequencing of Penicillium nordicum.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
CC -!- SIMILARITY: Belongs to the peptidase C56 family. HSP31-like subfamily.
CC {ECO:0000256|ARBA:ARBA00038493}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS45011.1}.
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DR EMBL; LHQQ01000050; KOS45011.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8PC00; -.
DR STRING; 229535.A0A0M8PC00; -.
DR OrthoDB; 4342at2759; -.
DR Proteomes; UP000037696; Unassembled WGS sequence.
DR GO; GO:0019172; F:glyoxalase III activity; IEA:UniProt.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000037696};
KW Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT DOMAIN 91..146
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 235 AA; 24449 MW; 1A316DD52E58E80A CRC64;
MAPKVLVVLT SHDKLGETGH PTGWYLPEFA HPHEVLHDKV SLTIASPNGG EAPLDPSSVK
ASESDELSQK FLKEQKALWT NTHKLADILP RADEFDALFY VGGHGPMFDL TNDPTSLALI
QTFAAANKPV AAVCHGPCVL LNAKAPSGVP LISGVGVTGF SNEEEDAVNL SAAMPFMLET
ELGRVTGGKY VKAAEAWGEM VVVGKAAGTG STIITGQNPG SATGVGKAIL KALGL
//
