ID A0A0M8SIR8_9ACTN Unreviewed; 784 AA.
AC A0A0M8SIR8;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:KOU34083.1};
GN ORFNames=ADK54_40875 {ECO:0000313|EMBL:KOU34083.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU34083.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC carbohydrate moieties of glycoproteins.
CC {ECO:0000256|ARBA:ARBA00004071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU34083.1}.
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DR EMBL; LGDD01000350; KOU34083.1; -; Genomic_DNA.
DR RefSeq; WP_053730913.1; NZ_LGDD01000350.1.
DR AlphaFoldDB; A0A0M8SIR8; -.
DR PATRIC; fig|1415557.3.peg.9005; -.
DR OrthoDB; 5526311at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR016286; FUC_metazoa-typ.
DR InterPro; IPR031919; Fucosidase_C.
DR InterPro; IPR000933; Glyco_hydro_29.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR Pfam; PF01120; Alpha_L_fucos; 1.
DR Pfam; PF16757; Fucosidase_C; 1.
DR PRINTS; PR00741; GLHYDRLASE29.
DR SMART; SM00812; Alpha_L_fucos; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..784
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005822554"
FT DOMAIN 705..781
FT /note="Alpha-L-fucosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16757"
SQ SEQUENCE 784 AA; 84715 MW; CE2BEB500BC97FA6 CRC64;
MTELPRRHVL GMTAGAAVGA ALLSPATADA NPLDPSTGVA AKGGEWGTVP AAVPVALDRW
FDNDGIDTAS ARGGDFDGSG YTFPGEQLPA GNVQLDGIPY VFPGAAAGVK NNIVALGQRI
DLPRGRYLSG LFLVASSYGD ASGRATVHYA DGSTSSAALG GPDWYSGSGQ LTAAYRYGPG
GVRDPHQVVV ASAELAMDPA REAVALTLPV TNPAQPGKPS LHVFALSLQP AANGRAVALR
DAHSTTTTLA SGAQSVEATV INAGTVTLLA SDGLSVQVDV DGARTVEAAR MPRLAPGEQA
RVRIGIRSGA GTAPGTVRPG RVTVRGRGQE AASVARQLTL GVPDFTPTDA SLSSHQAPYW
FQDAKFGIFI HWGVYSVPAW APVGVQYAEW YWAQMQDPNN ATYAYHRDTY GESFNYDDFI
PRFTAERFDP RSWVELFRDA GAQYHVLTSK HHEGFALWDT KVSDRNAVKM GPKKDLVRAL
FEASEQYAPQ LHRGLYFSMP EWFNPDSPWQ GHGPRNPYTL TPLPYTGYTP GKDYIKDLQA
PQMLELVEGY DPEILWCDIG GANDSHRVLA EYFNHAKNRS RPIEVTVNNR SGIGPHDFTT
PEYATYDTVV TAKWEASRGL DPFSYGYNQA TPDDRYMTTE EVVHTLVDIV SKNGNFLLDI
GPRADGTIPE IMQLRLRETG QWLKTNGEAI YGSTYWARMP QLGADLRFTV RQGRAFYIHS
LAKPGATLTV EAPVPIRAGD RVTMLGHGRP LTWRTSGSGL VIDVPAAARA AGSHAWVFKI
EWLG
//
