ID A0A0M8SLD1_9ACTN Unreviewed; 335 AA.
AC A0A0M8SLD1;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KOU35074.1};
GN ORFNames=ADK54_38390 {ECO:0000313|EMBL:KOU35074.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU35074.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU35074.1}.
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DR EMBL; LGDD01000339; KOU35074.1; -; Genomic_DNA.
DR RefSeq; WP_053730436.1; NZ_LGDD01000339.1.
DR AlphaFoldDB; A0A0M8SLD1; -.
DR PATRIC; fig|1415557.3.peg.8448; -.
DR OrthoDB; 3288692at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 11..67
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 335 AA; 35423 MW; 62E9A85401E325E9 CRC64;
MAEELTARAA VTSADVARLA GVSRATVSFV LNDTQAHRVS DSTRARVRAA ADQLGYVPHA
AARSLRAGRS NLVLMPASVS AVGRLVSTWL DDLHSELERH GYTTVLHAGR FSDAVGAARA
WAELRPAAVV ALDGGSLTAE AATVLRRAGV RAVVAFAARP VEGVHTIAFD HARIGALAVE
HLVSRGRTTI GVVMPKERGL DTFARPRLAG AESVAARSRA SVSAVELAYT RESAAELAAR
WRELGLDGVF AYNDEYAALL VRALQDEGIS VPDDVAVVGC DDLVLAALER PALTTVRLDL
PEPGRIADML HELVDTGTAP EMPGVEPMLV HRQSS
//
