ID A0A0M8SMP3_9ACTN Unreviewed; 377 AA.
AC A0A0M8SMP3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KOU35930.1};
GN ORFNames=ADK54_35820 {ECO:0000313|EMBL:KOU35930.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU35930.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU35930.1}.
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DR EMBL; LGDD01000328; KOU35930.1; -; Genomic_DNA.
DR RefSeq; WP_053730042.1; NZ_LGDD01000328.1.
DR AlphaFoldDB; A0A0M8SMP3; -.
DR PATRIC; fig|1415557.3.peg.7900; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF63; SENSOR HISTIDINE KINASE DESK; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KOU35930.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 172..238
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
SQ SEQUENCE 377 AA; 39770 MW; 22ED9A2B76B889FA CRC64;
MWQKLMWVGI WLAFMGAPIG DLLDGDHTTA ATVLGWLGLA TFVTVYLALV LRHTARPPAR
ATVYGLLGFL AALAVVLSLT LGSPWLVLFV YVSVSCGATL PMTLATWSIL VTTATMTVIG
TRATHVGDVV PGLVIPAILG GFAMTGVRHL IRTSVELREA RATVAQLAAN EERLRMARDL
HDLLGHSLSL ITLKSELAGR MLPGHPDQAA QQVADIEQVS RQALVDVRAA VSGYRRATLP
AELAGARTAL SAAGIEADVP TKAPEGLPAA EEEVLAWVLR EAATNVVRHS GARHCTVTIG
ERQTLDGRFL ELRVQDDGKP GPGPASPVPG NGLTGLAERL EKVSGVLETD SGRKGFTLVA
RIPLIPDPST TPLVSGS
//
