ID A0A0M8SS77_9ACTN Unreviewed; 468 AA.
AC A0A0M8SS77;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:KOU39035.1};
GN ORFNames=ADK54_27195 {ECO:0000313|EMBL:KOU39035.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU39035.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU39035.1}.
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DR EMBL; LGDD01000303; KOU39035.1; -; Genomic_DNA.
DR RefSeq; WP_053728360.1; NZ_LGDD01000303.1.
DR AlphaFoldDB; A0A0M8SS77; -.
DR PATRIC; fig|1415557.3.peg.5973; -.
DR OrthoDB; 594134at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 23..91
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 468 AA; 50590 MW; 8F5D47259317249C CRC64;
MVKSWATSPE TLGVDLHIDV GGAGLRSGLT DALREAVRSG RLTPGTRLPS SRSLAADLGI
ARNTVADAYA ELVAEGWLTA RQGSGTTVAQ RAVARPDRSH TRRLPTRRKP TYNLMAGSPD
LASFPRAEWL KAARRALTEA PHEAFGFGDP RGRVELRTVL ADYLARARGV YASPDRIVVC
SGFLHGLMLM AKVLRARRVR EVAVESYGLD FHWKVLTDAG LRTPPLPLDQ LGTRTQELGA
MKGAGAVLMT AAHQFPVGLP LLPDRRAAAV DWARTTGGLI VEDDYDGEFR YDRQPVGALQ
GLDPEHVVYI GTASKSLAPG LRLGWMVLPE HLADEVAQAK GGDWAGGALD QLTLAEFIRS
GAYDRHVRGM RLRYRRRRDQ LVTALAERAP EVRVSGIAAG LHALVELPPG TERSIIRAAT
FQGLALEGLS RYRHPELAPD RDALVVGYGT PPDSGWTGAL DALCNALP
//
