ID   A0A0M8THP8_9ACTN        Unreviewed;       308 AA.
AC   A0A0M8THP8;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=GDSL family lipase {ECO:0000313|EMBL:KOU55733.1};
GN   ORFNames=ADK57_43695 {ECO:0000313|EMBL:KOU55733.1};
OS   Streptomyces sp. MMG1533.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU55733.1, ECO:0000313|Proteomes:UP000037741};
RN   [1] {ECO:0000313|Proteomes:UP000037741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOU55733.1}.
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DR   EMBL; LGDG01000279; KOU55733.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8THP8; -.
DR   STRING; 1415546.ADK57_43695; -.
DR   PATRIC; fig|1415546.3.peg.9414; -.
DR   OrthoDB; 5503950at2; -.
DR   Proteomes; UP000037741; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   CDD; cd01823; SEST_like; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR037460; SEST-like.
DR   InterPro; IPR013830; SGNH_hydro.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   PANTHER; PTHR37981; LIPASE 2; 1.
DR   PANTHER; PTHR37981:SF1; SGNH_HYDRO DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13472; Lipase_GDSL_2; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR637460-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037741}.
FT   DOMAIN          38..293
FT                   /note="SGNH hydrolase-type esterase"
FT                   /evidence="ECO:0000259|Pfam:PF13472"
FT   ACT_SITE        42
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT   ACT_SITE        287
FT                   /evidence="ECO:0000256|PIRSR:PIRSR637460-1"
FT   DISULFID        59..86
FT                   /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT   DISULFID        137..159
FT                   /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
FT   DISULFID        217..266
FT                   /evidence="ECO:0000256|PIRSR:PIRSR637460-2"
SQ   SEQUENCE   308 AA;  32261 MW;  5AB10876D7E9933C CRC64;
     MLAGLLLACG TLAVAVGVTD DDTPAAEAKT ASKGPYVALG DSYTAGPEIP DRTGSPAGCD
     RSDRNYPALV AAGLGLKGAD FRDVSCSGAK ITDLTTSQST DDGTNPAQLK AISSDTRLVT
     VGIGGNDIGF SPMIKRCVGA GALYKLAGSG KYVSEDAPCA RQYAGDSGDS GDSVGQRIDE
     ADERLARTLT EVRRRAPQAR VYVVGYPAIL PSESAECDRE MSLAPGDVTF LRETEQRLNS
     MLRERAEAAG MGYVDTYTPS KGHDACSAED TRWIEPLVPR SPAAAMHPNE RGERGMADAV
     LHTLRSAL
//