ID   A0A0M8TM23_9ACTN        Unreviewed;       331 AA.
AC   A0A0M8TM23;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Delta fatty acid desaturase {ECO:0000313|EMBL:KOU59027.1};
GN   ORFNames=ADK57_35385 {ECO:0000313|EMBL:KOU59027.1};
OS   Streptomyces sp. MMG1533.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU59027.1, ECO:0000313|Proteomes:UP000037741};
RN   [1] {ECO:0000313|Proteomes:UP000037741}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00009295}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOU59027.1}.
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DR   EMBL; LGDG01000248; KOU59027.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8TM23; -.
DR   STRING; 1415546.ADK57_35385; -.
DR   PATRIC; fig|1415546.3.peg.7645; -.
DR   Proteomes; UP000037741; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd03506; Delta6-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
DR   PIRSF; PIRSF015921; FA_sphinglp_des; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          42..305
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   331 AA;  36985 MW;  FF6F46F025579336 CRC64;
     MSREVKRSGL LKRRPGYYSV KVGANLLLLA AGWTAFALIG QSWWQLLTAA FLAVMFTQTG
     FIGHDAGHHQ IAASKRVNDL LGRVHADLLI GLSYGWWIAK HNRHHSHPNH VDHDPDIADG
     AIAFTQDQAR VRRGAYAWLG RHQAWLFFPM LLLEGLALHV AGVKALFDGS GTRASLKSRV
     AQASLLTAHL VGYLTAVFWV LPPVQAVCFL LVHQGLFGLY MGCSFAPNHK GMPLFAKDDK
     IDFLRRQVLT SRNIRGHRVT DFALGGLNYQ IEHHLFPSMP RPSLRHAQEL VRTFCARHGI
     AYHETGLIDS YAQVLRHLHA VGGPLRPELE Y
//