ID A0A0M8TME3_9ACTN Unreviewed; 466 AA.
AC A0A0M8TME3;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=AraC family transcriptional regulator {ECO:0000313|EMBL:KOU61945.1};
GN ORFNames=ADK57_26030 {ECO:0000313|EMBL:KOU61945.1};
OS Streptomyces sp. MMG1533.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415546 {ECO:0000313|EMBL:KOU61945.1, ECO:0000313|Proteomes:UP000037741};
RN [1] {ECO:0000313|Proteomes:UP000037741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMG1533 {ECO:0000313|Proteomes:UP000037741};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU61945.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LGDG01000224; KOU61945.1; -; Genomic_DNA.
DR RefSeq; WP_053751991.1; NZ_LGDG01000224.1.
DR AlphaFoldDB; A0A0M8TME3; -.
DR STRING; 1415546.ADK57_26030; -.
DR PATRIC; fig|1415546.3.peg.5651; -.
DR OrthoDB; 9811249at2; -.
DR Proteomes; UP000037741; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.10.10; DNA Methylphosphotriester Repair Domain; 1.
DR Gene3D; 3.30.310.20; DNA-3-methyladenine glycosylase AlkA, N-terminal domain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR035451; Ada-like_dom_sf.
DR InterPro; IPR004026; Ada_DNA_repair_Zn-bd.
DR InterPro; IPR010316; AlkA_N.
DR InterPro; IPR037046; AlkA_N_sf.
DR InterPro; IPR011257; DNA_glycosylase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR PANTHER; PTHR43003; DNA-3-METHYLADENINE GLYCOSYLASE; 1.
DR PANTHER; PTHR43003:SF13; DNA-3-METHYLADENINE GLYCOSYLASE 2; 1.
DR Pfam; PF02805; Ada_Zn_binding; 1.
DR Pfam; PF06029; AlkA_N; 1.
DR Pfam; PF12833; HTH_18; 1.
DR SMART; SM01009; AlkA_N; 1.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF57884; Ada DNA repair protein, N-terminal domain (N-Ada 10); 1.
DR SUPFAM; SSF48150; DNA-glycosylase; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF55945; TATA-box binding protein-like; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000037741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 85..183
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000259|PROSITE:PS01124"
SQ SEQUENCE 466 AA; 49634 MW; F0773D0DF8F263E7 CRC64;
MDEDTRYEAV RSRDGRFDGE FFFAVETTGI YCRPSCPAVT PKRHNVRFFA TAAAAQGSGF
RACRRCRPDA VPGSAEWNVR ADVVGRAMRL IGDGVVDREG VAGLAARLGY SARQVQRQLT
AELGAGPVAL ARAQRAHTAR VLLQTTDLPI TQIAFASGFA SVRQFNDTMR DVYASTPSGL
RAAAPYGGRA SRRTATPSAG IPLRLAHRGP YRSGPVFDLL EAEAVAGVEE MSGARGRRTY
RRTLRLPHGT GIVAVDEQPG AARSASGAHP GGWLDARLHL TDPRDLTTAV QRLRRLFDLD
ADPYAVDERL GTDERLAPLV AARPGLRSPG AADPEELAVR ALVGRAEAER LVQRYGKTLD
APCGSLTHVF PEPAVLAGAE PDGTLGALTT ALADGAVRLD PGADRDDAEA ALLAVPGLDA
RTAATIRTRA LGDPDVAPPG PDTPDTWRPW RSYALQHLCA AGELAY
//
